Kalantar-Hormozi Abdolijalil, Mozafari Naser, Rasti Mehdi
Plastic Surgery, Shahid Beheshti Medical University, Tehran, Iran.
Aesthet Surg J. 2008 Mar-Apr;28(2):139-42. doi: 10.1016/j.asj.2007.12.005.
Although the "perfect" filler material to correct soft tissue facial defects, wrinkles, and scars has not yet been found, ideal characteristics for such a substance may be considered as the following: permanent, inert, malleable, easily injectable, quick to metabolize, not prone to infection, affordable, removable, nonmigratory, and not associated with any disorder or disease state as shown by clinical and paraclinical studies.
The authors present an evaluation of patients undergoing treatment for facial wrinkles or soft tissue defects by injection of polyacrylamide hydrogel (PAAG) and analyze outcomes on the basis of the incidence of moderate to severe complications.
A retrospective study was performed, including history taking, physical examination, and follow-up of 542 patients who received facial injections of PAAG.
Of 542 patients, 42 (7.7%) experienced complications such as swelling, abscess formation, lumpiness, change in facial appearance, change in gel location after injection, and sensitivity.
The authors recommend that complications from treatment with PAAG be studied further before widespread use of this soft tissue filler.
尽管尚未找到用于矫正面部软组织缺损、皱纹和瘢痕的“完美”填充材料，但此类物质的理想特性可被认为如下：永久性、惰性、可塑、易于注射、代谢迅速、不易感染、价格可承受、可移除、不迁移，且临床及临床旁研究表明不与任何病症或疾病状态相关。
作者对接受聚丙烯酰胺水凝胶（PAAG）注射治疗面部皱纹或软组织缺损的患者进行评估，并根据中重度并发症的发生率分析结果。
进行一项回顾性研究，包括对542例接受面部PAAG注射患者的病史采集、体格检查及随访。
542例患者中，42例（7.7%）出现并发症，如肿胀、脓肿形成、结块、面部外观改变、注射后凝胶位置改变及敏感。
作者建议在广泛使用这种软组织填充剂之前，进一步研究PAAG治疗的并发症。
