Christ Christophe, Brenke Rainer, Sattler Gerhard, Siems Werner, Novak Pavel, Daser A
Storz Medical AG, Tägerwilen, Switzerland.
Aesthet Surg J. 2008 Sep-Oct;28(5):538-44. doi: 10.1016/j.asj.2008.07.011.
Extracorporeal pulse activation therapy (EPAT), also called extracorporeal acoustic wave therapy, seeks to achieve effective and long-lasting improvement of age-related connective tissue weakness in the extremities, especially in the treatment of unsightly cosmetic skin defects referred to as cellulite.
The objective of this study was to stimulate metabolic activity in subcutaneous fat tissue by means of EPAT in order evaluate its effectiveness in enhancing connective tissue firmness and improving skin texture and structure.
Fifty-nine women with advanced cellulite were divided into 2 groups; one group of 15 patients received planar acoustic wave treatment for 6 therapy sessions within 3 weeks; a second group of 44 patients received 8 therapy sessions within 4 weeks. Changes in connective tissue were evaluated using the DermaScan C ultrasound system (Cortex Technology, Hadsund, Denmark). Skin elasticity measurements were performed using the DermaLab system (Cortex Technology). Photographs of treated areas were taken at each therapy session and at follow-up sessions.
Skin elasticity values gradually improved over the course of EPAT therapy and revealed a 73% increase at the end of therapy. At 3- and 6-month follow-ups, skin elasticity had even improved by 95% and 105%, respectively. Side effects included minor pain for 3 patients during therapy and slight skin reddening.
This study confirmed the effects of acoustic wave therapy on biologic tissue, including stimulation of microcirculation and improvement of cell permeability. Ultrasound evaluation demonstrated increased density and firmness in the network of collagen/elastic fibers in the dermis and subcutis. Treatment was most effective in older patients with a long history of cellulite.
体外脉冲激活疗法（EPAT），也称为体外声波疗法，旨在有效且持久地改善四肢与年龄相关的结缔组织薄弱状况，尤其是用于治疗被称为橘皮组织的不雅观的皮肤外观缺陷。
本研究的目的是通过EPAT刺激皮下脂肪组织的代谢活性，以评估其在增强结缔组织紧致度以及改善皮肤质地和结构方面的有效性。
59名患有严重橘皮组织的女性被分为两组；一组15名患者在3周内接受6次平面声波治疗；另一组44名患者在4周内接受8次治疗。使用DermaScan C超声系统（丹麦哈德孙的Cortex Technology公司）评估结缔组织的变化。使用DermaLab系统（Cortex Technology公司）进行皮肤弹性测量。在每次治疗期间和随访期间拍摄治疗区域的照片。
在EPAT治疗过程中，皮肤弹性值逐渐改善，在治疗结束时增加了73%。在3个月和6个月的随访中，皮肤弹性分别提高了95%和105%。副作用包括3名患者在治疗期间出现轻微疼痛以及皮肤轻微发红。
本研究证实了声波疗法对生物组织的作用，包括刺激微循环和改善细胞通透性。超声评估显示真皮和皮下组织中胶原/弹性纤维网络的密度和紧致度增加。该治疗对有长期橘皮组织病史的老年患者最为有效。
