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压迫性弹力袜治疗蜂窝组织炎的长波红外线辐射:一项临床双盲、随机、对照研究。

Long-wave infrared radiation reflected by compression stockings in the treatment of cellulite: a clinical double-blind, randomized and controlled study.

机构信息

Department of Dermatology, Federal University of São Paulo, R Borges Lagoa, 508, Sao Paulo, 04038-001, SP, Brazil.

出版信息

Int J Cosmet Sci. 2013 Oct;35(5):502-9. doi: 10.1111/ics.12073. Epub 2013 Jul 15.

Abstract

BACKGROUND

Cellulite refers to changes in skin relief on the thighs and buttocks of women, with a prevalence of 80-90%, causing dissatisfaction and search for treatment. Etiopathogenesis is multifactorial, as follows: herniation of the hypodermis towards the dermis, facilitated by perpendicular fibrous septa, changes in the dermal extracellular matrix, decreased adiponectin, genetic polymorphism, microcirculation alterations and inflammatory process. There are numerous therapeutic approaches, with little evidence of effectiveness. The long-wave infrared (LWIR) radiation interacts with water, improves microcirculation and stimulates metabolic processes. To date, the use of tissues with potential reflection of LWIR radiation has not been systematically investigated as adjuvant treatment for cellulite.

OBJECTIVE

To investigate the efficacy and safety of the treatment of cellulite through the use of compression stockings made with thread reflecting LWIR radiation.

PATIENTS AND METHODS

Clinical study of therapeutic intervention, controlled and double-blind, including 30 women, aging from 25 to 40 years, with cellulite of grades II and III on the thighs and buttocks who used compression stockings, "pantyhose" model, made with reflector thread of LWIR radiation, on only one randomized side. Women under other treatments for cellulite and with venous and/or blood insufficiencies were excluded. Evaluation of efficacy by clinical parameters, photographs, Dermatology Life Quality Index (DLQI), cutometry and high frequency ultrasonography and security by observation of adverse events and venous EcoDoppler recordings.

RESULTS

DLQI scores showed significant reduction; the two-dimensional high-frequency ultrasonography showed an insignificant increase in dermal echogenicity as well as other efficacy parameters demonstrated no or slight improvement, with no differences between the sides exposed or not to LWIR; and there were no severe adverse events.

CONCLUSION

Compression stockings, with or without thread reflector of LWIR, showed slight effects in the appearance of cellulite, but the treatment determined a positive impact on women quality of life.

摘要

背景

橘皮组织是指女性大腿和臀部皮肤凹陷的变化,其患病率为 80-90%,导致不满意和寻求治疗。病因学是多因素的,如下:皮下组织向真皮的疝出,垂直纤维隔促进,真皮细胞外基质的变化,脂联素减少,遗传多态性,微循环改变和炎症过程。有许多治疗方法,但有效性的证据很少。长波红外(LWIR)辐射与水相互作用,改善微循环并刺激代谢过程。迄今为止,尚未系统地研究具有 LWIR 辐射潜在反射的组织作为橘皮组织的辅助治疗。

目的

研究使用反射 LWIR 辐射的线程制成的压缩袜治疗橘皮组织的疗效和安全性。

患者和方法

包括 30 名年龄在 25 至 40 岁之间的患有 II 级和 III 级大腿和臀部橘皮组织的女性的治疗干预的临床研究,采用对照和双盲设计,这些女性使用反射 LWIR 辐射的线制成的压缩长筒袜,“连裤袜”模型,仅在一侧随机使用。排除正在接受其他橘皮组织治疗和静脉和/或血液不足的女性。通过临床参数、照片、皮肤病生活质量指数(DLQI)、皮肤测量术和高频超声以及通过观察不良事件和静脉 EcoDoppler 记录来评估安全性。

结果

DLQI 评分显著降低;二维高频超声显示真皮回声强度无明显增加,以及其他疗效参数显示无或轻微改善,暴露于或不暴露于 LWIR 的两侧无差异;没有严重的不良事件。

结论

有或没有 LWIR 反射线的压缩长筒袜在橘皮组织的外观上显示出轻微的效果,但该治疗方法对女性的生活质量产生了积极影响。

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