San-Martín Aurelio, Rovirosa Juana, Astudillo Luis, Sepúlveda Beatriz, Ruiz Daniela, San-Martín Carol
Departamento de Quimica, Facultad de Ciencias, Universidad de Chile, Santiago, Chile.
Nat Prod Res. 2008 Dec;22(18):1627-32. doi: 10.1080/14786410701869440.
Continued investigation of the marine alga Laurencia claviformis has led to the isolation of pacifenol, a halogenated sesquiterpene as the major metabolite. The microbial transformation of pacifenol is reported. It was cultivated with a marine strain of Penicillium brevicompactum yielding a new compound. The structure was elucidated on the basis of spectroscopic data. The anti-microbial activity of pacifenol derivatives is reported.
对海洋藻类棒状劳伦氏藻的持续研究已导致分离出太平洋醇，一种卤化倍半萜作为主要代谢产物。报道了太平洋醇的微生物转化。它与短密青霉的海洋菌株一起培养，产生了一种新化合物。根据光谱数据阐明了其结构。报道了太平洋醇衍生物的抗菌活性。
