Han Cheol-Min, Kim Hyoun-Ee, Kim Yong-Sik, Han Suk-Ku
Department of Materials Science and Engineering, Seoul National University, Seoul 151-744, Korea.
J Biomed Mater Res B Appl Biomater. 2009 Jul;90(1):165-70. doi: 10.1002/jbm.b.31270.
The biocompatibility of Co-Cr alloy was significantly improved by forming a rough TiO(2) layer on its surface. The TiO(2) layer was formed by coating the Co-Cr alloy with titanium (Ti) through electron beam deposition followed by microarc oxidation (MAO). When Ti was coated on the surface, the biocompatibility of the Co-Cr alloy was enhanced and it was further improved by the MAO treatment. There were close relationships between the phase, morphology, and thickness of the TiO(2) layer and the applied voltage. The biocompatibility of the specimens coated with Ti and subjected to MAO treatment was evaluated by in vitro alkaline phosphatase activity tests.
通过在其表面形成粗糙的TiO₂层，钴铬合金的生物相容性得到了显著改善。TiO₂层是通过电子束沉积法在钴铬合金上涂覆钛（Ti），然后进行微弧氧化（MAO）形成的。当在表面涂覆Ti时，钴铬合金的生物相容性得到增强，并且通过MAO处理进一步改善。TiO₂层的相、形态和厚度与施加电压之间存在密切关系。通过体外碱性磷酸酶活性测试评估涂覆Ti并进行MAO处理的试样的生物相容性。
