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通过纳米结构钛涂层改善钴铬合金的骨结合

Improving osseointegration of Co-Cr by nanostructured titanium coatings.

作者信息

Pham Vuong-Hung

机构信息

Advanced Institute for Science and Technology (AIST), Hanoi University of Science and Technology (HUST), No 01, Dai Co Viet road, Hanoi, Vietnam.

出版信息

Springerplus. 2014 Apr 21;3:197. doi: 10.1186/2193-1801-3-197. eCollection 2014.

DOI:10.1186/2193-1801-3-197
PMID:24809001
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4012034/
Abstract

This study reports the deposition of nanostructured Ti films on Co-Cr substrates to improve their surface characteristics and biocompatibility. The microstructure of the Ti films was controlled by application of negative substrate bias voltages. The surface roughness of Co-Cr implants was increased significantly after Ti coatings. The nanostructured Ti films are found to improve osteointergration of Co-Cr implants as indicated by enhancing cellular attachment, proliferation and differentiation, which was attributed mainly to the application of a biocompatible Ti coating, possessed a higher surface area for cell attachments and growth.

摘要

本研究报道了在钴铬基底上沉积纳米结构钛膜以改善其表面特性和生物相容性。通过施加负衬底偏压来控制钛膜的微观结构。钛涂层后，钴铬植入物的表面粗糙度显著增加。纳米结构钛膜被发现可改善钴铬植入物的骨整合，这表现为增强细胞附着、增殖和分化，这主要归因于应用了生物相容性钛涂层，其具有更高的细胞附着和生长表面积。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1d7e/4012034/2cc9eb683db3/40064_2014_924_Fig6_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1d7e/4012034/d1b9874669e2/40064_2014_924_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1d7e/4012034/4e78c399b5f2/40064_2014_924_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1d7e/4012034/bf80f56d8eb0/40064_2014_924_Fig3_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1d7e/4012034/40fef1f318ae/40064_2014_924_Fig4_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1d7e/4012034/2e4d4fa1f0f7/40064_2014_924_Fig5_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1d7e/4012034/2cc9eb683db3/40064_2014_924_Fig6_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1d7e/4012034/d1b9874669e2/40064_2014_924_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1d7e/4012034/4e78c399b5f2/40064_2014_924_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1d7e/4012034/bf80f56d8eb0/40064_2014_924_Fig3_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1d7e/4012034/40fef1f318ae/40064_2014_924_Fig4_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1d7e/4012034/2e4d4fa1f0f7/40064_2014_924_Fig5_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1d7e/4012034/2cc9eb683db3/40064_2014_924_Fig6_HTML.jpg

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本文引用的文献

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Deposition of TiN films on Co-Cr for improving mechanical properties and biocompatibility using reactive DC sputtering.采用反应直流磁控溅射在 Co-Cr 上沉积 TiN 薄膜以提高机械性能和生物相容性。
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