Department of Medicine, University College Hospital, Ibadan, Nigeria.
Eur J Neurol. 2009 Jan;16(1):54-62. doi: 10.1111/j.1468-1331.2008.02339.x.
No study using a stroke-specific measure has been previously conducted to determine the profile of health-related quality of life (HRQOL) in Nigerian stroke patients. Such a study is pre-requisite to planning of patient-centered rehabilitative care aimed at maximizing HRQOL improvement. Our objectives were to develop and validate a stroke-specific HRQOL measure, and determine the profile of HRQOL using it.
The HRQOL in stroke patients (HRQOLISP) questionnaire was developed and administered to 100 stroke patients and a control group of 100 age- and gender-matched healthy adults. The Stroke Levity Score (SLS) and modified Rankin Scale (mRS) were applied to measure stroke severity and disability respectively.
The HRQOLISP surpassed the Nunnaly's criterion for reliability and was able to discriminate between stroke (HRQOLsum = 73.5 +/- 9.1) and normal subjects (HRQOLsum = 84.4 +/- 6.9, P = 0.002). It differentiated strokes of various severities in the physical dimension (physical, psychological, cognitive and social domains). SLS and mRS correlated only to the domains in the physical dimension.
The HRQOLISP demonstrated good content, construct and discriminant validity and internal consistency reliability. Stroke had a multifaceted effect on HRQOL, which was more pronounced in the physical dimension.
此前尚无使用特定于中风的测量方法的研究来确定尼日利亚中风患者的健康相关生活质量（HRQOL）的特征。进行这样的研究是规划以患者为中心的康复护理的前提，目的是最大限度地提高 HRQOL 的改善。我们的目的是开发和验证一种特定于中风的 HRQOL 测量方法，并使用该方法确定 HRQOL 的特征。
开发了中风患者健康相关生活质量（HRQOLISP）问卷，并将其分发给 100 名中风患者和 100 名年龄和性别匹配的健康成年人对照组。应用中风严重程度评分（SLS）和改良 Rankin 量表（mRS）分别测量中风严重程度和残疾程度。
HRQOLISP 超过了 Nunnaly 的可靠性标准，能够区分中风（HRQOLsum = 73.5 +/- 9.1）和正常受试者（HRQOLsum = 84.4 +/- 6.9，P = 0.002）。它在身体维度（身体、心理、认知和社会领域）区分了各种严重程度的中风。SLS 和 mRS 仅与身体维度的各个领域相关。
HRQOLISP 表现出良好的内容、结构和区分效度以及内部一致性信度。中风对 HRQOL 有多种影响，在身体维度上更为明显。
