Department of Medicine, University College Hospital, Ibadan, Nigeria WFNR-Blossom Center for Neurorehabilitation, Ibadan, Nigeria.
NeuroRehabilitation. 2013;33(2):241-50. doi: 10.3233/NRE-130951.
There is lack of a German-language holistic stroke-specific health-related quality of life (HRQOL) measure with therapeutically-oriented domains. The objective of this study was to investigate the psychometric properties of the HRQOL in stroke patients (HRQOLISP) questionnaire in German stroke survivors.
Following standard procedure for cross-cultural validation, the HRQOLISP was translated into German. It was completed by 103 German stroke patients and 50 apparently healthy controls. Acceptance, ceiling and floor effects, reliability, as well as content, construct, factorial and known-group's validity were analysed. Stratification was according to modified Rankin, stroke levity and National Institute of Health stroke scales.
The HRQOLISP was acceptable and holistic with neither ceiling nor floor effect. One-factor solution explained >40% of the variance for most domains. Two-factor solution explained 82% of the variance for the global HRQOL consistent with the conceptual framework distributing the therapeutically-oriented domains into two spheres. Cronbach's α ranged from 0.77 to 0.92 for the domains. The HRQOLISP, though lengthy, covered the entire spectrum of stroke-related HRQOL with no additional item suggested by the German stroke patients. The HRQOLISP demonstrated good convergent and discriminant validity as well as excellent 'known groups' validity across disability and stroke severity strata.
The German version of the HRQOLISP is the first holistic, stroke-specific HRQOLISP measures with therapeutically-oriented domains to be validated in Germany. It is acceptable, reliable and valid but needs to be validated in proxies to facilitate its utility among stroke patients with severe communication problems.
目前缺乏一种具有治疗导向领域的德语整体脑卒中特定健康相关生活质量（HRQOL）测量方法。本研究的目的是调查德国脑卒中幸存者中 HRQOLISP 问卷的心理测量特性。
按照跨文化验证的标准程序，将 HRQOLISP 翻译成德语。由 103 名德国脑卒中患者和 50 名明显健康的对照组完成。分析了接受度、天花板和地板效应、可靠性以及内容、结构、因子和已知组的有效性。分层是根据改良 Rankin、脑卒中严重程度和美国国立卫生研究院脑卒中量表进行的。
HRQOLISP 是可接受的，整体上没有天花板或地板效应。对于大多数领域，单因素解决方案解释了 >40%的方差。两因素解决方案解释了全球 HRQOL 的 82%的方差，与将治疗导向领域分为两个领域的概念框架一致。各领域的克朗巴赫的α值范围为 0.77 至 0.92。HRQOLISP 虽然冗长，但涵盖了与脑卒中相关的 HRQOL 的整个范围，德国脑卒中患者没有提出任何额外的项目。HRQOLISP 表现出良好的收敛和区分有效性以及出色的“已知组”有效性，跨越残疾和脑卒中严重程度的分层。
HRQOLISP 的德语版本是第一个在德国验证的具有治疗导向领域的整体、特定于脑卒中的 HRQOL 测量方法。它是可接受的、可靠的和有效的，但需要在代理中进行验证，以方便在有严重沟通问题的脑卒中患者中使用。
