University College Hospital, Ibadan, Nigeria.
Neurorehabil Neural Repair. 2010 Nov-Dec;24(9):814-25. doi: 10.1177/1545968310369113. Epub 2010 Sep 16.
A recent review showed that no existing instrument measured the entire spectrum of health-related quality of life (HRQOL) in stroke patients. However, the HRQOL in stroke patients (HRQOLISP) questionnaire is valid and exceptionally comprehensive. Founded on a holistic model of human life, it comprises both physical and spiritual spheres. However, its 102-item length may discourage routine use. Therefore, the aim was to determine the psychometric attributes of a shortened version based on a multicultural transnational study.
HRQOLISP was administered to 100 stroke patients in Ibadan, 103 in Berlin, and control groups of 100 apparently healthy adults in Ibadan and 50 in Berlin. Analyzing data from both cities, items were reduced to 40. Construct validity of the resulting HRQOLISP-40 was assessed by comparison with the National Institutes of Health Stroke Scale (NIHSS), Stroke Levity Scale (SLS), modified Rankin Scale (mRS), and Short Form 36 (SF-36) Health Survey.
In multicultural settings, the HRQOLISP-40 showed good internal consistency (α = .76, .86) and test-retest reliability. It retained its discriminant validity between stroke and healthy participants and demonstrated good "known-groups" validity in its relationship to the SLS, NIHSS, and mRS in the physical sphere. The physical sphere showed good convergent validity with corresponding facets of the SF-36.
Despite item reduction, the HRQOLISP-40 demonstrated excellent psychometric properties and is valid for routine use and clinical trials in stroke. The relative preservation of the spiritual sphere demonstrated the concept of disability disparity. Its ability to simultaneously assess the physical and spiritual spheres may be beneficial in studies aimed at potentiating internal adaptation in stroke patients.
最近的一项综述表明，目前尚无任何工具能全面评估卒中患者的健康相关生活质量（HRQOL）。然而，HRQOLISP 问卷具有有效性和极高的全面性。它以人类生活的整体模式为基础，包含身体和精神领域。但其 102 个条目的长度可能会阻碍其常规使用。因此，本研究旨在通过一项多文化跨国研究，确定基于该问卷的简化版本的心理测量属性。
在伊巴丹对 100 名卒中患者、柏林对 103 名卒中患者和伊巴丹对照组的 100 名健康成年人及柏林对照组的 50 名健康成年人进行 HRQOLISP 问卷调查。对来自两个城市的数据进行分析，将条目数量减少至 40。通过与 NIHSS、SLS、mRS 和 SF-36 健康调查的比较，评估所得 HRQOLISP-40 的结构有效性。
在多文化环境中，HRQOLISP-40 显示出良好的内部一致性（α=.76，.86）和重测信度。它保留了卒中患者与健康参与者之间的判别效度，并在与 SLS、NIHSS 和 mRS 等物理领域的关系中显示出良好的“已知群体”有效性。物理领域与 SF-36 的相应方面显示出良好的聚合效度。
尽管进行了条目删减，HRQOLISP-40 仍具有优异的心理测量学特性，可用于卒中患者的常规使用和临床试验。精神领域的相对保留证明了残疾差异的概念。它同时评估身体和精神领域的能力可能有益于研究增强卒中患者的内在适应能力。
