Vincent-Onabajo Grace O, Owolabi Mayowa O, Hamzat Talhatu K
Department of Medical Rehabilitation (Physiotherapy), University of Maiduguri , Borno State , Nigeria .
Disabil Rehabil. 2014;36(12):1014-9. doi: 10.3109/09638288.2013.825652. Epub 2013 Aug 20.
To investigate the sensitivity and responsiveness of the Health-Related Quality of Life in Stroke Patients-40 (HRQOLISP-40) scale in evaluating stroke patients from onset to 12 months.
Fifty-five patients with first-incidence stroke were followed-up for 12 months. The HRQOLISP-40 scale was used to assess health-related quality of life (HRQOL) while stroke severity was assessed with the Stroke Levity Scale. Sensitivity to change was assessed by analyzing changes in the HRQOLISP-40 scores between pairs of months with paired samples t-test. Standardized effect size (SES) and standardized response mean (SRM) were used to express responsiveness.
Overall HRQOL and domains in the physical sphere of the HRQOLISP-40 were sensitive to change at different time intervals in the first 12 months post-stroke. Marked responsiveness (SES and SRM >0.7) was demonstrated by the overall scale, and the physical, psycho-emotional and cognitive domains at varying time intervals. For instance, SRM was greater than 0.7 between 1 and 6, 3 and 12, 1 and 9, and 1 and 12 months for both the physical and psycho-emotional domains.
The HRQOLISP-40 is a sensitive and responsive stroke-specific quality of life measure that can be used to evaluate the outcome of stroke rehabilitation.
Enhancing the health-related quality of life (HRQOL) of stroke survivors can be regarded as the ultimate goal of stroke rehabilitation. Sensitive and responsive stroke-specific HRQOL measures are required for use in evaluative studies, and clinical trials and practice. The Health-Related Quality of Life in Stroke Patients-40 (HRQOLISP-40) is a sensitive and responsive stroke-specific scale.
探讨卒中患者健康相关生活质量量表-40（HRQOLISP-40）在评估卒中患者从发病至12个月期间的敏感性和反应性。
对55例首次发生卒中的患者进行了12个月的随访。采用HRQOLISP-40量表评估健康相关生活质量（HRQOL），同时用卒中严重程度量表评估卒中严重程度。通过配对样本t检验分析HRQOLISP-40评分在各月之间的变化来评估变化敏感性。采用标准化效应量（SES）和标准化反应均值（SRM）来表示反应性。
卒中后12个月内，HRQOLISP-40的总体HRQOL及身体领域的各个维度在不同时间间隔对变化敏感。总体量表以及身体、心理情绪和认知领域在不同时间间隔均表现出显著的反应性（SES和SRM>0.7）。例如，身体和心理情绪领域在1至6个月、3至12个月、1至9个月以及1至12个月之间的SRM均大于0.7。
HRQOLISP-40是一种敏感且具有反应性的卒中特异性生活质量测量工具，可用于评估卒中康复的效果。
提高卒中幸存者的健康相关生活质量（HRQOL）可被视为卒中康复的最终目标。在评估研究、临床试验及实践中需要使用敏感且具有反应性的卒中特异性HRQOL测量工具。卒中患者健康相关生活质量量表-40（HRQOLISP-40）是一种敏感且具有反应性的卒中特异性量表。
