Razafindratsimandresy Richter, Jeanmaire Elisabeth M, Counor Dorian, Vasconcelos Pedro Fernando, Sall Amadou Alpha, Reynes Jean-Marc
Unité de virologie, Institut Pasteur de Madagascar, route de l'Institut Pasteur, BP 1274, Antananarivo 101, Madagascar.
J Gen Virol. 2009 Jan;90(Pt 1):44-7. doi: 10.1099/vir.0.006825-0.
Herpesviruses have previously been isolated from African and South-American bats. Recently, herpesviruses detected from European insectivorous bats (family Vespertilionidae) were classified molecularly as betaherpesviruses and gammaherpesviruses. In the current study, we performed PCR analyses targeting the UL30 catalytic subunit region of the DNA polymerase gene of the African and South American herpesviruses and new Malagasy and Cambodian herpesviruses isolated from bats, especially frugivorous bats from the families Pteropodidae and Phyllostomidae. The sequences obtained from the amplified products indicated that these isolates belonged to the genus Simplexvirus of the subfamily Alphaherpesvirinae. These results extend the taxonomic range of bat herpesviruses with the description of four members in the subfamily Alphaherpesvirinae. Furthermore, these data confirm and extend the geographical distribution of herpesvirus in bats to three more continents (Africa, South America and Asia) and indicate the presence of these viruses in frugivorous bats of the families Pteropodidae and Phyllostomidae.
疱疹病毒此前已从非洲和南美洲的蝙蝠中分离出来。最近，从欧洲食虫蝙蝠（蝙蝠科）中检测到的疱疹病毒在分子水平上被分类为β疱疹病毒和γ疱疹病毒。在本研究中，我们针对非洲和南美洲疱疹病毒以及从蝙蝠，特别是果蝠科和叶口蝠科的食果蝙蝠中分离出的新的马达加斯加和柬埔寨疱疹病毒的DNA聚合酶基因的UL30催化亚基区域进行了PCR分析。从扩增产物中获得的序列表明，这些分离株属于α疱疹病毒亚科的单纯疱疹病毒属。这些结果扩展了蝙蝠疱疹病毒的分类范围，描述了α疱疹病毒亚科中的四个成员。此外，这些数据证实并将疱疹病毒在蝙蝠中的地理分布扩展到另外三个大陆（非洲、南美洲和亚洲），并表明这些病毒存在于果蝠科和叶口蝠科的食果蝙蝠中。
