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本文引用的文献

1
Identification of a bile-induced exopolysaccharide required for Salmonella biofilm formation on gallstone surfaces.鉴定一种胆汁诱导的胞外多糖，其为沙门氏菌在胆结石表面形成生物膜所必需。
Infect Immun. 2008 Nov;76(11):5341-9. doi: 10.1128/IAI.00786-08. Epub 2008 Sep 15.
2
Adaptation and response of Bifidobacterium animalis subsp. lactis to bile: a proteomic and physiological approach.动物双歧杆菌乳亚种对胆汁的适应性及反应：蛋白质组学和生理学方法
Appl Environ Microbiol. 2007 Nov;73(21):6757-67. doi: 10.1128/AEM.00637-07. Epub 2007 Sep 7.
3
Impact of environmental and genetic factors on biofilm formation by the probiotic strain Lactobacillus rhamnosus GG.环境和遗传因素对益生菌鼠李糖乳杆菌GG生物膜形成的影响。
Appl Environ Microbiol. 2007 Nov;73(21):6768-75. doi: 10.1128/AEM.01393-07. Epub 2007 Sep 7.
4
Cell envelope changes in Bifidobacterium animalis ssp. lactis as a response to bile.动物双歧杆菌乳亚种中细胞包膜对胆汁的应答变化
FEMS Microbiol Lett. 2007 Sep;274(2):316-22. doi: 10.1111/j.1574-6968.2007.00854.x. Epub 2007 Jul 25.
5
Bile salts enhance bacterial co-aggregation, bacterial-intestinal epithelial cell adhesion, biofilm formation and antimicrobial resistance of Bacteroides fragilis.胆汁盐可增强脆弱拟杆菌的细菌共聚集、细菌与肠上皮细胞的黏附、生物膜形成及抗菌耐药性。
Microb Pathog. 2007 Aug-Sep;43(2-3):78-87. doi: 10.1016/j.micpath.2007.04.002. Epub 2007 Apr 20.
6
Screening of exopolysaccharide-producing Lactobacillus and Bifidobacterium strains isolated from the human intestinal microbiota.从人体肠道微生物群中分离出的产胞外多糖的乳酸杆菌和双歧杆菌菌株的筛选。
Appl Environ Microbiol. 2007 Jul;73(13):4385-8. doi: 10.1128/AEM.02470-06. Epub 2007 May 4.
7
Induction of alpha-L-arabinofuranosidase activity by monomeric carbohydrates in Bifidobacterium longum and ubiquity of encoding genes.长双歧杆菌中单体碳水化合物对α-L-阿拉伯呋喃糖苷酶活性的诱导及编码基因的普遍性
Arch Microbiol. 2007 Feb;187(2):145-53. doi: 10.1007/s00203-006-0181-x. Epub 2006 Oct 10.
8
The F1F0-ATPase of Bifidobacterium animalis is involved in bile tolerance.动物双歧杆菌的F1F0-ATP酶与胆汁耐受性有关。
Environ Microbiol. 2006 Oct;8(10):1825-33. doi: 10.1111/j.1462-2920.2006.01067.x.
9
Exopolysaccharides produced by probiotic strains modify the adhesion of probiotics and enteropathogens to human intestinal mucus.益生菌菌株产生的胞外多糖会改变益生菌和肠道病原体对人肠黏液的黏附。
J Food Prot. 2006 Aug;69(8):2011-5. doi: 10.4315/0362-028x-69.8.2011.
10
Bile acids stimulate biofilm formation in Vibrio cholerae.胆汁酸刺激霍乱弧菌生物膜的形成。
Mol Microbiol. 2006 Jan;59(1):193-201. doi: 10.1111/j.1365-2958.2005.04846.x.

胆汁会影响动物双歧杆菌胞外多糖的合成。

Bile affects the synthesis of exopolysaccharides by Bifidobacterium animalis.

作者信息

Ruas-Madiedo Patricia, Gueimonde Miguel, Arigoni Fabrizio, de los Reyes-Gavilán Clara G, Margolles Abelardo

机构信息

Instituto de Productos Lácteos de Asturias (IPLA-CSIC), Carretera de Infiesto s/n 33300 Villaviciosa, Asturias, Spain.

出版信息

Appl Environ Microbiol. 2009 Feb;75(4):1204-7. doi: 10.1128/AEM.00908-08. Epub 2008 Dec 16.

DOI:10.1128/AEM.00908-08
PMID:19088310
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2643586/
Abstract

By using cryo-scanning electron microscopy and quantification with lectin-conjugated probes, we have detected the production of exopolysaccharides (EPS) in Bifidobacterium animalis subsp. lactis in the presence of bile. In addition, the expression of gtf01207, which codifies a putative priming glycosyltransferase involved in EPS synthesis, was induced by bile.

摘要

通过使用低温扫描电子显微镜以及用凝集素偶联探针进行定量分析，我们检测到在胆汁存在的情况下，动物双歧杆菌乳酸亚种中胞外多糖（EPS）的产生。此外，编码一种推测参与EPS合成的起始糖基转移酶的gtf01207的表达受胆汁诱导。