Duranti Sabrina, Longhi Giulia, Ventura Marco, van Sinderen Douwe, Turroni Francesca
Laboratory of Probiogenomics, Department of Chemistry, Life Sciences and Environmental Sustainability, University of Parma, Parco Area delle Scienze 11a, 43124 Parma, Italy.
GenProbio srl, 43124 Parma, Italy.
Microorganisms. 2020 Dec 22;9(1):8. doi: 10.3390/microorganisms9010008.
The mammalian gut is densely inhabited by microorganisms that have coevolved with their host. Amongst these latter microorganisms, bifidobacteria represent a key model to study host-microbe interaction within the mammalian gut. Remarkably, bifidobacteria naturally occur in a range of ecological niches that are either directly or indirectly connected to the animal gastrointestinal tract. They constitute one of the dominant bacterial members of the intestinal microbiota and are among the first colonizers of the mammalian gut. Notably, the presence of bifidobacteria in the gut has been associated with several health-promoting activities. In this review, we aim to provide an overview of current knowledge on the genetic diversity and ecology of bifidobacteria. Furthermore, we will discuss how this important group of gut bacteria is able to colonize and survive in the mammalian gut, so as to facilitate host interactions.
哺乳动物的肠道中密集地栖息着与宿主共同进化的微生物。在这些微生物中，双歧杆菌是研究哺乳动物肠道内宿主与微生物相互作用的关键模型。值得注意的是，双歧杆菌自然存在于一系列与动物胃肠道直接或间接相连的生态位中。它们是肠道微生物群的主要细菌成员之一，也是哺乳动物肠道最早的定植菌之一。值得注意的是，肠道中双歧杆菌的存在与多种促进健康的活动有关。在这篇综述中，我们旨在概述目前关于双歧杆菌遗传多样性和生态学的知识。此外，我们将讨论这群重要的肠道细菌如何能够在哺乳动物肠道中定植和存活，从而促进与宿主的相互作用。
