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用于磁粒子成像的轨迹分析。

Trajectory analysis for magnetic particle imaging.

作者信息

Knopp T, Biederer S, Sattel T, Weizenecker J, Gleich B, Borgert J, Buzug T M

机构信息

Institute of Medical Engineering, University of Lübeck, Lübeck, Germany.

出版信息

Phys Med Biol. 2009 Jan 21;54(2):385-97. doi: 10.1088/0031-9155/54/2/014. Epub 2008 Dec 19.

Abstract

Recently a new imaging technique called magnetic particle imaging was proposed. The method uses the nonlinear response of magnetic nanoparticles when a time varying magnetic field is applied. Spatial encoding is achieved by moving a field-free point through an object of interest while the field strength in the vicinity of the point is high. A resolution in the submillimeter range is provided even for fast data acquisition sequences. In this paper, a simulation study is performed on different trajectories moving the field-free point through the field of view. The purpose is to provide mandatory information for the design of a magnetic particle imaging scanner. Trajectories are compared with respect to density, speed and image quality when applied in data acquisition. Since simulation of the involved physics is a time demanding task, moreover, an efficient implementation is presented utilizing caching techniques.

摘要

最近,一种名为磁粒子成像的新成像技术被提了出来。该方法利用了施加随时间变化的磁场时磁性纳米颗粒的非线性响应。通过在感兴趣的物体中移动一个无场点来实现空间编码,此时该点附近的场强较高。即使对于快速数据采集序列,也能提供亚毫米范围内的分辨率。本文针对在视野范围内移动无场点的不同轨迹进行了模拟研究。目的是为磁粒子成像扫描仪的设计提供必要信息。在数据采集中应用时,将根据密度、速度和图像质量对轨迹进行比较。此外,由于所涉及物理过程的模拟是一项耗时的任务,因此还提出了一种利用缓存技术的高效实现方法。

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