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多药及毒素排出(MATE)家族中的多药外排转运蛋白

Multidrug efflux transporters in the MATE family.

作者信息

Kuroda Teruo, Tsuchiya Tomofusa

机构信息

Department of Genome Applied Microbiology, Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University, Tsushima, Okayama 700-8530, Japan.

出版信息

Biochim Biophys Acta. 2009 May;1794(5):763-8. doi: 10.1016/j.bbapap.2008.11.012. Epub 2008 Dec 6.

Abstract

The MATE (Multidrug And Toxic Compound Extrusion) family is the most recently categorized one among five multidrug efflux transporter families. As far as we know, about twenty MATE transporters have been characterized so far. According to the information in sequence databases, huge numbers of MATE transporters seem to be present in various microorganisms. In this review, we would like to summarize the properties of the MATE-family transporters.

摘要

多药及毒性化合物外排(MATE)家族是五个多药外排转运蛋白家族中最新分类的一个。据我们所知,到目前为止已鉴定出约20种MATE转运蛋白。根据序列数据库中的信息,各种微生物中似乎存在大量的MATE转运蛋白。在本综述中,我们将总结MATE家族转运蛋白的特性。

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