Ikeda Tamon, Inamori Masahiko, Fujisawa Nobutaka, Iwasaki Tomoyuki, Akiyama Tomoyuki, Akimoto Keiko, Mawatari Hironori, Iida Hiroshi, Endo Hiroki, Nozaki Yuichi, Sakamoto Yasunari, Fujita Koji, Takahashi Hirokazu, Yoneda Masato, Yoneda Kyoko, Goto Ayumu, Abe Yasunobu, Kirikoshi Hiroyuki, Kobayashi Noritoshi, Kubota Kensuke, Saito Satoru, Nakajima Atsushi
Gastroenterology Division, Yokohama City University Hospital, 3-9 Fukuura, Kanazawa-ku, Yokohama, 236-0004, Japan.
Hepatogastroenterology. 2008 Sep-Oct;55(86-87):1905-7.
BACKGROUND/AIMS: The aim of this study was to determine whether there was a correlation between body positions and gastric emptying, using a novel non-invasive technique for measuring gastric emptying with a continuous real time 13C breath test (BreathID system).
Ten healthy male volunteers participated in this randomized, two-way crossover study. On both occasions, the 13C breath test was performed for 4 hours using the BreathID system with a liquid meal (200 kcal per 200 mL) containing 100 mg 13C-acetic acid. Subjects were randomly assigned to sit comfortable (the sitting position) or to lie supine (the lying position).
In the lying position, T 1/2 and T lag were significantly delayed. The gastric emptying coefficient was also decreased in lying position.
This study showed that gastric emptying following a liquid meal was significantly delayed in the lying position compared to the sitting position, suggesting the potential use of these findings in the clinical setting for patients receiving enteral nutrition via the stomach.
背景/目的：本研究旨在使用一种新型非侵入性技术——连续实时13C呼气试验（BreathID系统）测量胃排空，以确定身体姿势与胃排空之间是否存在相关性。
10名健康男性志愿者参与了这项随机、双向交叉研究。在两种情况下，均使用BreathID系统对含有100mg 13C-乙酸的流食（每200mL含200千卡）进行4小时的13C呼气试验。受试者被随机分配为舒适坐姿（坐姿）或仰卧位（躺姿）。
在躺姿时，T1/2和Tlag显著延迟。躺姿时胃排空系数也降低。
本研究表明，与坐姿相比，流食后躺姿时的胃排空明显延迟，这表明这些发现可能在临床中用于经胃接受肠内营养的患者。
