体位对肠内营养时胃排空的影响：一项使用连续实时¹³C呼气试验（BreathID系统）的交叉研究

Effects of body positions on gastric emptying with enteral nutrition: a crossover study using a continuous real time 13C breath test (BreathID system).

作者信息

Ikeda Tamon, Inamori Masahiko, Fujisawa Nobutaka, Iwasaki Tomoyuki, Akiyama Tomoyuki, Akimoto Keiko, Mawatari Hironori, Iida Hiroshi, Endo Hiroki, Nozaki Yuichi, Sakamoto Yasunari, Fujita Koji, Takahashi Hirokazu, Yoneda Masato, Yoneda Kyoko, Goto Ayumu, Abe Yasunobu, Kirikoshi Hiroyuki, Kobayashi Noritoshi, Kubota Kensuke, Saito Satoru, Nakajima Atsushi

机构信息

Gastroenterology Division, Yokohama City University Hospital, 3-9 Fukuura, Kanazawa-ku, Yokohama, 236-0004, Japan.

出版信息

Hepatogastroenterology. 2008 Sep-Oct;55(86-87):1905-7.

PMID:19102419

Abstract

BACKGROUND/AIMS: The aim of this study was to determine whether there was a correlation between body positions and gastric emptying, using a novel non-invasive technique for measuring gastric emptying with a continuous real time 13C breath test (BreathID system).

METHODOLOGY

Ten healthy male volunteers participated in this randomized, two-way crossover study. On both occasions, the 13C breath test was performed for 4 hours using the BreathID system with a liquid meal (200 kcal per 200 mL) containing 100 mg 13C-acetic acid. Subjects were randomly assigned to sit comfortable (the sitting position) or to lie supine (the lying position).

RESULTS

In the lying position, T 1/2 and T lag were significantly delayed. The gastric emptying coefficient was also decreased in lying position.

CONCLUSIONS

This study showed that gastric emptying following a liquid meal was significantly delayed in the lying position compared to the sitting position, suggesting the potential use of these findings in the clinical setting for patients receiving enteral nutrition via the stomach.

摘要

背景/目的：本研究旨在使用一种新型非侵入性技术——连续实时13C呼气试验（BreathID系统）测量胃排空，以确定身体姿势与胃排空之间是否存在相关性。