Kubik Stefan
Fachbereich Chemie-Organische Chemie, Technische Universität Kaiserslautern, Erwin-Schrödinger-Strasse, 67663 Kaiserslautern, Germany.
Angew Chem Int Ed Engl. 2009;48(10):1722-5. doi: 10.1002/anie.200805497.
Improving on Mother Nature? The carbohydrate recognition demonstrated by supramolecular systems in water can now compete with that of natural systems, both in terms of affinity and selectivity. A synthetic carbohydrate receptor displays similar affinity for N-acetyl-D-glucosamine derivatives as the lectin wheat germ agglutinin and even greater selectivity (see picture: gray C, white H, blue N, red O).
超越自然母亲?目前,超分子体系在水中展现出的碳水化合物识别能力,在亲和力和选择性方面都能与天然体系相媲美。一种合成碳水化合物受体对N-乙酰-D-葡萄糖胺衍生物的亲和力与凝集素麦胚凝集素相似,甚至具有更高的选择性(见图:灰色为碳,白色为氢,蓝色为氮,红色为氧)。