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Evidence of Circulation of Several HAV Genetic Variants and Emergence of Potential Antigenic Variants in an Endemo-Epidemic Country before Vaccine Introduction.在引入疫苗之前，在一个地方性流行国家存在几种 HAV 遗传变异和潜在抗原变异的证据。
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Hepatitis a virus infection in Central-West Tunisia: an age structured model of transmission and vaccination impact.突尼斯中西部地区甲型肝炎病毒感染：传播和疫苗接种影响的年龄结构模型。
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Comparison of the Prevalence and Risk Factors of Hepatitis A in 10 to 18-Year-Old Adolescents of Sixteen Iranian Provinces: The CASPIAN-III Study.伊朗16个省份10至18岁青少年甲型肝炎患病率及危险因素比较：里海-III研究
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本文引用的文献

1
Sexually transmitted diseases treatment guidelines 2002. Centers for Disease Control and Prevention.《2002年性传播疾病治疗指南》。疾病控制与预防中心。
MMWR Recomm Rep. 2002 May 10;51(RR-6):1-78.
2
Effectiveness of hepatitis A vaccine in a former frequently affected community: 9 years' followup after the Monroe field trial of VAQTA.
Vaccine. 2002 Mar 15;20(13-14):1699-701. doi: 10.1016/s0264-410x(02)00042-7.
3
Quantification and duration of viraemia during hepatitis A infection as determined by real-time RT-PCR.通过实时逆转录聚合酶链反应确定甲型肝炎感染期间病毒血症的定量及持续时间。
J Viral Hepat. 2002 Mar;9(2):101-6. doi: 10.1046/j.1365-2893.2002.00336.x.
4
Control of hepatitis A through routine vaccination of children.通过对儿童进行常规疫苗接种来控制甲型肝炎。
JAMA. 2001 Dec 19;286(23):2968-73. doi: 10.1001/jama.286.23.2968.
5
Seroprevalence of hepatitis A virus markers in Eastern Saudi Arabia.沙特阿拉伯东部甲型肝炎病毒标志物的血清流行率。
Saudi Med J. 2000 Oct;21(10):945-9.
6
Change in hepatitis A virus seroepidemiology in southern Taiwan: a large percentage of the population lack protective antibody.台湾南部甲型肝炎病毒血清流行病学的变化：很大一部分人口缺乏保护性抗体。
J Med Virol. 2001 Jun;64(2):104-8. doi: 10.1002/jmv.1024.
7
The changing epidemiological pattern of hepatitis A in an urban population of India: emergence of a trend similar to the European countries.印度城市人口中甲肝流行病学模式的变化：呈现出与欧洲国家相似的趋势。
Eur J Epidemiol. 2000 Jun;16(6):507-10. doi: 10.1023/a:1007628021661.
8
Hepatitis A.甲型肝炎
Infect Dis Clin North Am. 2000 Sep;14(3):605-15. doi: 10.1016/s0891-5520(05)70123-9.
9
Hepatitis A shifting epidemiology in the Middle East and Africa.中东和非洲甲型肝炎流行病学的变化
Vaccine. 2000 Feb 18;18 Suppl 1:S65-7. doi: 10.1016/s0264-410x(99)00468-5.
10
Hepatitis A shifting epidemiology in South-East Asia and China.东南亚和中国甲型肝炎流行病学的变化
Vaccine. 2000 Feb 18;18 Suppl 1:S61-4. doi: 10.1016/s0264-410x(99)00467-3.

科威特甲型肝炎病毒的血清流行病学

Seroepidemiology of hepatitis A virus in Kuwait.

作者信息

Alkhalidi Jameela, Alenezi Bader, Al-Mufti Seham, Hussain Entisar, Askar Haifa, Kemmer Nyingi, Neff Guy W

机构信息

Thuniyan Al-Ghanim, GI Center & University of Kuwait, Safat, Kuwait.

出版信息

World J Gastroenterol. 2009 Jan 7;15(1):102-5. doi: 10.3748/wjg.15.102.

DOI:10.3748/wjg.15.102
PMID:19115474
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2653286/
Abstract

AIM

To find the current seroepidemiology of hepatitis A virus (HAV) in Kuwait.

METHODS

A total of 2851 Kuwaitis applying for new jobs were screened.

RESULTS

HAV-positive cases were 28.8%; 59% were males and 41% were females. The highest prevalence was in the Ahmadi area. High prevalence was among the group of non-educated rather than educated parents. This is the first study in Kuwait demonstrating the shifting epidemiology of HAV.

CONCLUSION

This study reflects the need of the Kuwaiti population for an HAV vaccine.

摘要

目的

了解科威特甲型肝炎病毒（HAV）的当前血清流行病学情况。

方法

对2851名申请新工作的科威特人进行了筛查。

结果

HAV阳性病例占28.8%；男性占59%，女性占41%。最高患病率出现在艾哈迈迪地区。非受过教育的父母群体中的患病率高于受过教育的父母群体。这是科威特第一项证明HAV流行病学变化的研究。

结论

本研究反映了科威特人群对HAV疫苗的需求。