来自阿氏席藻CYA 126/8的含高酪氨酸的蓝藻肽880和960以及鱼腥藻肽908和915
Homotyrosine-containing cyanopeptolins 880 and 960 and anabaenopeptins 908 and 915 from Planktothrix agardhii CYA 126/8.
作者信息
Okumura Hilary S, Philmus Benjamin, Portmann Cyril, Hemscheidt Thomas K
机构信息
Department of Chemistry, University of Hawaii, 2545 McCarthy Mall, Honolulu, Hawaii 96822, USA.
出版信息
J Nat Prod. 2009 Jan;72(1):172-6. doi: 10.1021/np800557m.
Abstract
Two homotyrosine-bearing cyanopeptolins are described from Planktothrix agardhii CYA 126/8. The compounds feature a common homotyrosine-containing cyclohexadepsipeptide and differ by sulfation of an exocyclically located 2-O-methyl-d-glyceric acid residue. In addition we describe two anabaenopeptins, which contain two homotyrosine residues, one of which is N-methylated. The anabaenopeptins have a common cyclopentapeptide portion and differ in the amino acid linked to it via an ureido bond, arginine and tyrosine, respectively.
摘要
从阿氏浮丝藻CYA 126/8中鉴定出两种含高酪氨酸的蓝藻肽。这些化合物具有一个共同的含高酪氨酸的环己缩肽，区别在于一个环外位置的2-O-甲基-D-甘油酸残基的硫酸化修饰。此外，我们还描述了两种鱼腥藻肽，它们含有两个高酪氨酸残基，其中一个是N-甲基化的。这两种鱼腥藻肽具有一个共同的环五肽部分，区别在于通过脲基键与之相连的氨基酸，分别为精氨酸和酪氨酸。
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