Velasquez-Mieyer Pedro, Neira Claudia P, Nieto Ramfis, Cowan Patricia A
Dept. of Pediatrics, LeBonheur Children's Medical Center, 50 North Dunlap, Memphis, TN 38103, USA.
Ther Adv Cardiovasc Dis. 2007 Oct;1(1):61-81. doi: 10.1177/1753944707082800.
The cardiometabolic syndrome is highly prevalent among overweight youth. The risk of developing the cardiometabolic syndrome is likely triggered or exacerbated by concurrent obesity, unhealthy lifestyle/eating habits, and hormonal changes (puberty). Current screening recommendations include measurement of blood pressure, fasting insulin and glucose, and total cholesterol. However, limiting assessments to these measures underestimates cardiometabolic risk in overweight youth, particularly minorities. Early identification of cardiometabolic risk in its incipient stages may justify early and more aggressive intervention to prevent progression and complications. This review provides rationale for additional assessments to determine cardiometabolic risk in overweight youth and recommends treatment options.
心脏代谢综合征在超重青少年中极为普遍。并发肥胖、不健康的生活方式/饮食习惯以及激素变化（青春期）可能引发或加剧患心脏代谢综合征的风险。当前的筛查建议包括测量血压、空腹胰岛素和血糖以及总胆固醇。然而，将评估局限于这些指标会低估超重青少年，尤其是少数族裔的心脏代谢风险。在心脏代谢风险的初始阶段尽早识别，可能有助于采取早期且更积极的干预措施，以防止病情进展和并发症的发生。本综述为确定超重青少年心脏代谢风险的额外评估提供了理论依据，并推荐了治疗方案。
