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土耳其成人过敏症的患病率及风险因素(PARFAIT):一项多中心横断面成人研究的结果

Prevalence and Risk Factors of Allergies in Turkey (PARFAIT): results of a multicentre cross-sectional study in adults.

作者信息

Kurt E, Metintas S, Basyigit I, Bulut I, Coskun E, Dabak S, Deveci F, Fidan F, Kaynar H, Kunt Uzaslan E, Onbasi K, Ozkurt S, Pasaoglu Karakis G, Sahan S, Sahin U, Oguzulgen K, Yildiz F, Mungan D, Yorgancioglu A, Gemicioglu B, Fuat Kalyoncu A

机构信息

Eskisehir Osmangazi University, Pulmonary Diseases-Allergy Dept, Eskisehir, Turkey.

出版信息

Eur Respir J. 2009 Apr;33(4):724-33. doi: 10.1183/09031936.00082207. Epub 2009 Jan 7.

DOI:10.1183/09031936.00082207
PMID:19129285
Abstract

The Prevalence and Risk Factors of Allergies in Turkey (PARFAIT) study was planned to evaluate the prevalence of and risk factors for asthma and allergic diseases in Turkey. The present analysis used data from 25,843 parents of primary school children, obtained from a cross-sectional questionnaire-based study. A total of 25,843 questionnaires from 14 centres were evaluated. In rural areas, the prevalences asthma, wheezing, allergic rhinitis and eczema in males were: 8.5% (95% confidence interval (CI) 7.9-9.1%), 13.5% (95% CI 12.8-14.2%), 17.5% (95% CI 16.7-18.2%) and 10.8% (95% CI 10.2-11.4%), respectively; and in females were: 11.2% (95% CI 10.9-11.8%), 14.7% (95% CI 14.3-15.1%), 21.2% (95% CI 20.4-22.0%) and 13.1% (95% CI 12.4-13.8%), respectively. In urban areas, the corresponding prevalences in males were: 6.2% (95% CI 5.8-6.6%), 10.8% (95% CI 10.3-11.3%), 11.7% (95% CI 11.4-12.0%) and 6.6% (95% CI 6.2-7.0%), respectively; and in females were: 7.5 % (95% CI 7.9-7.1%), 12.0% (95% CI 11.7-12.3%), 17.0% (95% CI 16.4-17.6%) and 7.3% (95% CI 6.9-7.7%), respectively. Having an atopic first-degree relative or any other atopic diseases had significant effects on the prevalence of allergic diseases. Housing conditions, such as living in a shanty-type house, visible moulds at home and use of wood or biomass as heating or cooking material were associated with one or more allergic diseases. Although genetic susceptibility is strongly associated, country- and population-based environmental factors may contribute to increased prevalence rates of allergic diseases.

摘要

土耳其过敏症的患病率及风险因素(PARFAIT)研究旨在评估土耳其哮喘和过敏性疾病的患病率及风险因素。本分析使用了一项基于问卷调查的横断面研究中25843名小学生家长的数据。共评估了来自14个中心的25843份问卷。在农村地区,男性哮喘、喘息、过敏性鼻炎和湿疹的患病率分别为:8.5%(95%置信区间[CI] 7.9 - 9.1%)、13.5%(95% CI 12.8 - 14.2%)、17.5%(95% CI 16.7 - 18.2%)和10.8%(95% CI 10.2 - 11.4%);女性的患病率分别为:11.2%(95% CI 10.9 - 11.8%)、14.7%(95% CI 14.3 - 15.1%)、21.2%(95% CI 20.4 - 22.0%)和13.1%(95% CI 12.4 - 13.8%)。在城市地区,男性相应的患病率分别为:6.2%(95% CI 5.8 - 6.6%)、10.8%(95% CI 10.3 - 11.3%)、11.7%(95% CI 11.4 - 12.0%)和6.6%(95% CI 6.2 - 7.0%);女性的患病率分别为:7.5%(95% CI 7.9 - 7.1%)、12.0%(95% CI 11.7 - 12.3%)、17.0%(95% CI 16.4 - 17.6%)和7.3%(95% CI 6.9 - 7.7%)。有特应性一级亲属或任何其他特应性疾病对过敏性疾病的患病率有显著影响。住房条件,如居住在棚户式房屋、家中可见霉菌以及使用木材或生物质作为取暖或烹饪材料,与一种或多种过敏性疾病相关。尽管遗传易感性密切相关,但基于国家和人群的环境因素可能导致过敏性疾病患病率上升。

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