Hacettepe University Faculty of Medicine, Pediatric Allergy and Asthma Unit, Ankara, Turkey.
J Investig Allergol Clin Immunol. 2011;21(4):270-7.
Little is known about the epidemiology of atopic eczema (AE), and studies from the Mediterranean region and the Middle East are limited.
We investigated the frequency, burden, and risk factors of AE in a developing country.
The International Study of Asthma and Allergies in Childhood Phase II questionnaire was used to survey a representative sample of 10 to 11-year-old children in Turkey. Children were examined by allergists, and parents completed standardized questionnaires.
Among 6755 children, the prevalence of having eczema during one's lifetime or currently was 17.1% and 8.1%, respectively. The prevalence of visits to the doctor, nocturnal awakening, school absenteeism, and drug usage was 36.3%, 56%, 9.7%, and 28.7%, respectively. Associated factors were current rhinoconjunctivitis (odds ratio [OR], 2.53; 95% confidence interval [CI], 1.99-3.21), current wheezing (OR, 2.10; 95% CI, 1.58-2.79), family history of allergic disease (OR, 1.62; 95% CI, 1.21-2.18), low birth weight (OR, 1.79; 95% CI, 1.08-2.94), and exposure to animals in the first year of life (OR, 1.47; 95% CI, 1.06-2.03).
In a developing Mediterranean country, the prevalence of AE is comparable to that of developed countries in the same region and lower than that observed in developed countries elsewhere. The course of the disease and risk factors of AE probably differ in developing countries.
特应性皮炎（AE）的流行病学知识有限，且来自地中海地区和中东的研究也很有限。
我们调查了一个发展中国家 AE 的频率、负担和危险因素。
采用国际儿童哮喘和过敏研究第二期问卷，对土耳其 10 至 11 岁儿童进行代表性抽样调查。由过敏专家对儿童进行检查，父母填写标准化问卷。
在 6755 名儿童中，终生或当前患有湿疹的比例分别为 17.1%和 8.1%。就诊、夜间觉醒、缺课和用药的比例分别为 36.3%、56%、9.7%和 28.7%。相关因素为当前鼻结膜炎（比值比[OR]，2.53；95%置信区间[CI]，1.99-3.21）、当前喘息（OR，2.10；95%CI，1.58-2.79）、过敏疾病家族史（OR，1.62；95%CI，1.21-2.18）、低出生体重（OR，1.79；95%CI，1.08-2.94）和生命第一年接触动物（OR，1.47；95%CI，1.06-2.03）。
在一个发展中的地中海国家，AE 的患病率与该地区发达国家相当，低于其他发达国家。AE 的疾病进程和危险因素在发展中国家可能不同。
