Turk J Med Sci. 2019 Apr 18;49(2):551-557. doi: 10.3906/sag-1807-229.
BACKGROUND/AIM: Non-cystic fibrosis bronchiectasis (non-CF BR) is common in developing countries.Limited data are available regarding the impact of atopy, and no data are available regarding allergic rhinitis in patients with adult bronchiectasis.The aim of this study was to evaluate the prevalence of atopy and allergic rhinitis in the clinical conditions of patients with BR.
The study enrolled 101 patients who were diagnosed with non-CF BR using high-resolution computed chest tomography. Allergic rhinitis (AR) was defined by skin prick test (SPT) positivity and the presence of any nasal symptoms (watery runny nose, nasal obstruction, nasal itching, and sneezing).
The mean age of patients was 48 ± 15 years (range 18–82); 55 (54.5%) patients were female. SPT positivity was detected in 37 (36.6%) cases. AR was detected in 32 (31.7%) patients with non-CF BR. AR was related to dyspnea (P = 0.04) and number of admissions to an emergency department in the previous year (P = 0.01). Forced expiratory volume in 1 s and forced vital capacity in patients with and without AR were different (P = 0.01 and P = 0.01, respectively). AR was correlated with number of admissions to an emergency department in the last year (r = 0.417, P = 0.005).
We concluded that atopy was detected in more than one-third of adult non-CF BR patients. This study demonstrated that non-CF BR patients might have AR; it might be important to be aware of nasal symptoms in non-CF BR patients.
背景/目的：非囊性纤维化性支气管扩张症（非 CF BR）在发展中国家较为常见。有关特应性的影响的数据有限，而关于成人支气管扩张症患者过敏性鼻炎的数据则尚无报道。本研究旨在评估 BR 患者临床状况下特应性和过敏性鼻炎的患病率。
本研究纳入了 101 例经高分辨率计算机胸部 CT 诊断为非 CF BR 的患者。过敏性鼻炎（AR）的定义为皮肤点刺试验（SPT）阳性和存在任何鼻部症状（水样流涕、鼻塞、鼻痒和打喷嚏）。
患者的平均年龄为 48 ± 15 岁（范围 18-82）；55 例（54.5%）为女性。37 例（36.6%）患者 SPT 阳性。32 例（31.7%）非 CF BR 患者检出 AR。AR 与呼吸困难（P=0.04）和前一年急诊就诊次数有关（P=0.01）。AR 患者和无 AR 患者的 1 秒用力呼气量和用力肺活量存在差异（P=0.01 和 P=0.01）。AR 与前一年急诊就诊次数相关（r=0.417，P=0.005）。
我们得出结论，三分之一以上的成人非 CF BR 患者存在特应性。本研究表明，非 CF BR 患者可能患有 AR；在非 CF BR 患者中注意鼻部症状可能很重要。
