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一名患有囊性纤维化的婴儿的慢性代谢性碱中毒。

Chronic metabolic alkalosis in an infant with cystic fibrosis.

作者信息

Eigenmann P, Délèze G, Kuchler H

机构信息

Department of Paediatrics, Regional Hospital, Sion, Switzerland.

出版信息

Eur J Pediatr. 1991 Jul;150(9):669-70. doi: 10.1007/BF02072631.

DOI:10.1007/BF02072631
PMID:1915522
Abstract

A 6-month-old infant suffering from cystic fibrosis is reported. In spite of an apparently appropriate treatment and in absence of respiratory infection, the patient showed progressive anorexia, intermittent vomiting and weight loss. These non-specific signs and symptoms could all be explained by metabolic alkalosis and disappeared immediately after oral supplementation with sodium and potassium chloride. This unusual metabolic complication should be searched for in every cystic fibrosis infant with unexplained anorexia and failure to thrive.

摘要

报告了一名患有囊性纤维化的6个月大婴儿。尽管进行了看似适当的治疗且无呼吸道感染,但该患者仍出现进行性厌食、间歇性呕吐和体重减轻。这些非特异性体征和症状都可以用代谢性碱中毒来解释,口服补充氯化钠和氯化钾后症状立即消失。对于每一名患有不明原因厌食和发育不良的囊性纤维化婴儿,都应排查这种不寻常的代谢并发症。

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1
Chronic metabolic alkalosis in an infant with cystic fibrosis.一名患有囊性纤维化的婴儿的慢性代谢性碱中毒。
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[Dehydration and metabolic alkalosis: an unusual presentation of cystic fibrosis in an infant].[脱水与代谢性碱中毒:婴儿期囊性纤维化的一种不寻常表现]
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Chloride deficiency as a presentation or complication of cystic fibrosis.氯缺乏作为囊性纤维化的一种表现或并发症。
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Cystic fibrosis presenting with recurrent vomiting and metabolic alkalosis.以反复呕吐和代谢性碱中毒为表现的囊性纤维化。
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[Cystic fibrosis revealed by dehydration with hypochloronatremic alkalosis in 3 infants and a neonate].[3例婴儿及1例新生儿因脱水伴低氯性碱中毒而确诊的囊性纤维化]
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Cystic fibrosis presenting with chronic electrolyte depletion, metabolic alkalosis and hyperaldosteronism.囊性纤维化表现为慢性电解质耗竭、代谢性碱中毒和醛固酮增多症。
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Metabolic alkalosis in infants with cystic fibrosis.患有囊性纤维化的婴儿中的代谢性碱中毒。
Pediatrics. 1979 Sep;64(3):389.

引用本文的文献

1
Electrolyte abnormalities in cystic fibrosis: systematic review of the literature.囊性纤维化中的电解质异常:文献系统综述
Pediatr Nephrol. 2014 Jun;29(6):1015-23. doi: 10.1007/s00467-013-2712-4. Epub 2013 Dec 11.

本文引用的文献

1
Heat prostration in fibrocystic disease of the pancreas and other conditions.
Pediatrics. 1951 Nov;8(5):648-56.
2
Changing feeding trends as a cause of electrolyte depletion in infants with cystic fibrosis.喂养方式的改变作为囊性纤维化婴儿电解质耗竭的一个原因
Pediatrics. 1981 Aug;68(2):203-7.
3
Early diagnosis of cystic fibrosis by means of sweat microosmometry.
J Pediatr. 1984 May;104(5):691-4. doi: 10.1016/s0022-3476(84)80945-2.
4
Metabolic alkalosis in cystic fibrosis.
囊性纤维化中的代谢性碱中毒。
J Pediatr. 1971 Dec;79(6):930-6. doi: 10.1016/s0022-3476(71)80186-5.
5
Metabolic alkalosis and salt depletion in cystic fibrosis.囊性纤维化中的代谢性碱中毒和盐耗竭。
J Pediatr. 1973 Mar;82(3):535-6. doi: 10.1016/s0022-3476(73)80139-8.
6
Developmental outcome in children exposed to chloride-deficient formula.接触低氯配方奶粉儿童的发育结局。
Pediatrics. 1987 Jun;79(6):851-7.
7
Hypoelectrolytemia and metabolic alkalosis in infants with cystic fibrosis.囊性纤维化婴儿的低电解质血症和代谢性碱中毒
Pediatrics. 1979 Apr;63(4):580-3.