Ranjitkar S, Rodriguez J M, Kaidonis J A, Richards L C, Townsend G C, Bartlett D W
School of Dentistry, The University of Adelaide, Adelaide, SA 5005, Australia.
J Dent. 2009 Apr;37(4):250-4. doi: 10.1016/j.jdent.2008.11.013. Epub 2009 Jan 20.
In addition to its role as a remineralizing agent in preventing dental caries, calcium product (CPP-ACP) delivered as a mousse (Tooth Mousse, TM) can reduce erosion of enamel and dentine. The aim of this study was to determine whether CPP-ACP could also reduce erosive tooth wear involving toothbrush abrasion.
Flat, polished enamel and dentine specimens (n=72) were subjected to 10 wear regimes, with each regime involving erosion in 0.3% citric acid (pH 3.2) for 10 min followed by toothbrush abrasion in a slurry of fluoride-free toothpaste and artificial saliva (1:3 ratio by weight) under a load of 2N for 200 cycles. The specimens were immersed in artificial saliva for 2h between wear regimes. In the experimental group 1, TM (containing CPP-ACP) was applied at the beginning of each wear episode for 5 min whereas TM- (without CPP-ACP) was applied in the experimental group 2. No mousse was applied in the control group.
TM significantly reduced enamel wear (mean+/-S.E., 1.26+/-0.33 microm in the experimental group 1 vs 3.48+/-0.43 microm in the control group) and dentine wear (2.16+/-0.89 microm in the experimental group 1 vs 10.29+/-1.64 microm in the control group), and dentine wear was significantly less in the experimental group 1 than in the experimental group 2 (5.75+/-0.98 microm).
The finding that TM reduced erosive tooth wear involving toothbrush abrasion, probably by remineralizing and lubricating eroded tooth surfaces, may have implications in the management of tooth wear.
除了作为预防龋齿的再矿化剂发挥作用外，以慕斯形式提供的钙产品（酪蛋白磷酸肽 - 无定形磷酸钙，CPP - ACP）（护齿慕斯，TM）可以减少牙釉质和牙本质的侵蚀。本研究的目的是确定CPP - ACP是否也能减少涉及牙刷磨损的侵蚀性牙齿磨损。
将扁平、抛光的牙釉质和牙本质标本（n = 72）进行10种磨损模式处理，每种模式包括在0.3%柠檬酸（pH 3.2）中侵蚀10分钟，然后在无氟牙膏和人工唾液的浆液（重量比1:3）中，在2N负荷下进行200次循环的牙刷磨损。在不同磨损模式之间，将标本浸入人工唾液中2小时。在实验组1中，每次磨损开始时应用TM（含CPP - ACP）5分钟，而在实验组2中应用不含CPP - ACP的TM - 。对照组不应用慕斯。
TM显著减少了牙釉质磨损（实验组1平均±标准误为1.26±0.33微米，对照组为3.48±0.43微米）和牙本质磨损（实验组1为2.16±0.89微米，对照组为10.29±1.64微米），并且实验组1的牙本质磨损显著低于实验组2（5.75±0.98微米）。
TM减少了涉及牙刷磨损的侵蚀性牙齿磨损，可能是通过对被侵蚀的牙齿表面进行再矿化和润滑，这一发现可能对牙齿磨损的管理有影响。
