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[牡丹皮不同部位活性成分含量测定及指纹图谱研究]

[Studies on content determination and fingerprint of active constituents in different parts of cortex moutan].

作者信息

Zhou Gang, Lv Qing-Hong

机构信息

Center for Drug Evaluation, State Food and Drug Administration, Beijing 100038, China.

出版信息

Zhongguo Zhong Yao Za Zhi. 2008 Sep;33(18):2070-3.

Abstract

OBJECTIVE

To determine the chemical constituents in different parts of Cortex Moutan, which can provides evidences to the processing techniques of Cortex Moutan.

METHOD

The contents of paeonol, peoniflorin and fingerprints in different parts of Cortex Moutan were determined by HPLC.

RESULT

Compareed with phloem, paeonol in cork is twice as many, but paeonol in duramen is half as many peoniflorin in cork is half and four times as many, peoniflorin in duramen is twice as many, the contents of active ingredients in duramen are high in fingerprint.

CONCLUSION

If we only abandon the core, then we may get simple processings with the active ingredient contents increasing.

摘要

目的

测定牡丹皮不同部位的化学成分,为牡丹皮炮制工艺提供依据。

方法

采用高效液相色谱法测定牡丹皮不同部位丹皮酚、芍药苷的含量及指纹图谱。

结果

与韧皮部相比,栓皮中丹皮酚含量是其两倍,但木心部丹皮酚含量仅为其一半;栓皮中芍药苷含量是其一半,木心部芍药苷含量是其四倍;指纹图谱显示木心部有效成分含量较高。

结论

仅去除木心,可简化炮制工艺并提高有效成分含量。

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