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[牡丹皮不同部位活性成分含量测定及指纹图谱研究]

[Studies on content determination and fingerprint of active constituents in different parts of cortex moutan].

作者信息

Zhou Gang, Lv Qing-Hong

机构信息

Center for Drug Evaluation, State Food and Drug Administration, Beijing 100038, China.

出版信息

Zhongguo Zhong Yao Za Zhi. 2008 Sep;33(18):2070-3.

PMID:19160786
Abstract

OBJECTIVE

To determine the chemical constituents in different parts of Cortex Moutan, which can provides evidences to the processing techniques of Cortex Moutan.

METHOD

The contents of paeonol, peoniflorin and fingerprints in different parts of Cortex Moutan were determined by HPLC.

RESULT

Compareed with phloem, paeonol in cork is twice as many, but paeonol in duramen is half as many peoniflorin in cork is half and four times as many, peoniflorin in duramen is twice as many, the contents of active ingredients in duramen are high in fingerprint.

CONCLUSION

If we only abandon the core, then we may get simple processings with the active ingredient contents increasing.

摘要

目的

测定牡丹皮不同部位的化学成分,为牡丹皮炮制工艺提供依据。

方法

采用高效液相色谱法测定牡丹皮不同部位丹皮酚、芍药苷的含量及指纹图谱。

结果

与韧皮部相比,栓皮中丹皮酚含量是其两倍,但木心部丹皮酚含量仅为其一半;栓皮中芍药苷含量是其一半,木心部芍药苷含量是其四倍;指纹图谱显示木心部有效成分含量较高。

结论

仅去除木心,可简化炮制工艺并提高有效成分含量。

相似文献

1
[Studies on content determination and fingerprint of active constituents in different parts of cortex moutan].[牡丹皮不同部位活性成分含量测定及指纹图谱研究]
Zhongguo Zhong Yao Za Zhi. 2008 Sep;33(18):2070-3.
2
[Simultaneous determination of three active constituents in cortex moutan by RP-HPLC].[反相高效液相色谱法同时测定牡丹皮中三种活性成分]
Zhongguo Zhong Yao Za Zhi. 2006 Oct;31(20):1699-701.
3
[The quality control of carbonized cortex moutan].[碳化牡丹皮的质量控制]
Zhong Yao Cai. 2007 Dec;30(12):1502-5.
4
[Dynamic analysis of major active ingredients of Cortex Moutan cultivated in Dianjiang county of Chongqing].[重庆垫江县栽培牡丹皮主要活性成分的动态分析]
Zhongguo Zhong Yao Za Zhi. 2007 Aug;32(15):1501-4.
5
[Rapid identification of compounds in cortex moutan by liquid chromatography-tandem mass spectrometry].[液相色谱-串联质谱法快速鉴定牡丹皮中的化合物]
Yao Xue Xue Bao. 2006 Sep;41(9):852-6.
6
[Study on the influence of the contents of paeonol in the cutting process of fresh Cortex Moutan].[丹皮酚含量对鲜牡丹皮切制过程的影响研究]
Zhong Yao Cai. 2012 Jun;35(6):883-6.
7
Comparative pharmacokinetic study of paeoniflorin after oral administration of pure paeoniflorin, extract of Cortex Moutan and Shuang-Dan prescription to rats.芍药苷在大鼠口服纯芍药苷、牡丹皮提取物及双丹方后的比较药代动力学研究。
J Ethnopharmacol. 2009 Sep 25;125(3):444-9. doi: 10.1016/j.jep.2009.07.019. Epub 2009 Jul 25.
8
[Studies on HPLC fingerprint of cortex moutan].[牡丹皮高效液相色谱指纹图谱的研究]
Zhongguo Zhong Yao Za Zhi. 2006 Oct;31(20):1677-80.
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[RP-HPLC determination of main chemical components in different parts and different harvest periods of Paeonia lactiflora].[反相高效液相色谱法测定芍药不同部位及不同采收期的主要化学成分]
Yao Xue Xue Bao. 2010 Apr;45(4):489-93.
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[Study on preparation and determination of Liaojin plastics].[疗金涂膜剂的制备与测定研究]
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Liquid Chromatography-diode Array Detector-electrospray Mass Spectrometry and Principal Components Analyses of Raw and Processed Moutan Cortex.
生熟牡丹皮的液相色谱-二极管阵列检测器-电喷雾质谱联用及主成分分析
Pharmacogn Mag. 2016 Jan-Mar;12(45):50-6. doi: 10.4103/0973-1296.176046.