对称性控制着DNA多面体的表面几何形状。

Symmetry controls the face geometry of DNA polyhedra.

作者信息

Zhang Chuan, Ko Seung Hyeon, Su Min, Leng Yujun, Ribbe Alexander E, Jiang Wen, Mao Chengde

机构信息

Department of Chemistry, Markey Center for Structural Biology and Department of Biological Sciences, Purdue University, West Lafayette, Indiana 47907, USA.

出版信息

J Am Chem Soc. 2009 Feb 4;131(4):1413-5. doi: 10.1021/ja809666h.

DOI:10.1021/ja809666h

PMID:19173666

Abstract

Two complementary strategies have been developed to control the face geometry during the self-assembly of DNA polyhedra from branched DNA nanomotifs (tiles). In these approaches, any two interacting tiles are not equivalent in terms of either sequence or orientation; thus, each face must contain an even number of tiles. As a demonstration, DNA cubes, whose each face contains four tiles, have been assembled through these approaches.

摘要

为了在由分支DNA纳米基元（瓦片）自组装DNA多面体的过程中控制其表面几何形状，人们开发了两种互补策略。在这些方法中，任何两个相互作用的瓦片在序列或取向上都不相同；因此，每个面必须包含偶数个瓦片。作为一个示例，通过这些方法已经组装出了每个面包含四个瓦片的DNA立方体。