Kao Tze-Wah, Lai Mei-Shu, Tsai Tun-Jun, Jan Chyi-Feng, Chie Wei-Chu, Chen Wan-Yu
Division of Nephrology, Department of Internal Medicine, National Taiwan University Hospital and National Taiwan University College of Medicine, Taipei, Taiwan.
Artif Organs. 2009 Jan;33(1):61-8. doi: 10.1111/j.1525-1594.2008.00675.x.
This study evaluated the associations between economic, social, psychological factors, and health-related quality of life of hemodialysis patients. Cross-sectional study design was used. End-stage renal disease patients who had received maintenance hemodialysis for more than 2 months at 14 centers in northern Taiwan were invited to participate. Demographic, economic, and psychosocial data of patients were collected. Depression was assessed by the Beck Depression Inventory. Health-related quality of life was measured by the Medical Outcomes Study Short-Form 36. Multivariable linear regression analyses were performed. Eight hundred sixty-one patients (373 males, mean age 59.4 +/- 13.2 years) completed the study. Higher monthly income was positively associated with role emotional and mental health (P < 0.05), and so was increased frequency of social activities with social functioning (P < 0.05). The more worries, the stronger the inverse associations with social functioning (P < 0.05) and mental health (P < 0.01). Higher depression scores were associated with lower scores of all Short-Form 36 dimensions (P < 0.01). Higher monthly income and increased social activities are associated with better health-related quality of life, whereas more worries and higher depression scores are associated with worse health-related quality of life of hemodialysis patients.
本研究评估了经济、社会、心理因素与血液透析患者健康相关生活质量之间的关联。采用横断面研究设计。邀请了在台湾北部14个中心接受维持性血液透析超过2个月的终末期肾病患者参与。收集了患者的人口统计学、经济和社会心理数据。通过贝克抑郁量表评估抑郁情况。通过医学结局研究简表36来测量健康相关生活质量。进行了多变量线性回归分析。861名患者(373名男性,平均年龄59.4±13.2岁)完成了研究。较高的月收入与角色情感和心理健康呈正相关(P<0.05),社交活动频率增加与社会功能也呈正相关(P<0.05)。担忧越多,与社会功能(P<0.05)和心理健康(P<0.01)的负相关越强。较高的抑郁得分与简表36所有维度的较低得分相关(P<0.01)。较高的月收入和增加的社交活动与血液透析患者更好的健康相关生活质量相关,而更多的担忧和较高的抑郁得分与更差的健康相关生活质量相关。