Gao Yun-Tao, Zhang Wen-Bin, Yang Li-Rong, Wang Xue-Mei, Yang Yi-Lin
School of Chemistry and Bio-Science, Yunnan Nationalities University, Kunming 650031, China.
Zhong Yao Cai. 2008 Sep;31(9):1399-402.
Scavening effects of panax notoginseng saponins on active oxygen species in the systems of Fenton reaction, autoxidation of pyrogallol and riboflavine photosensitization were investigated by the mean of spectrophotometry. The inhibition of panax notoginseg saponins on the damage of DNA chain induced by hydroxyl radical by panax notoginseng saponins was observed by the mean of gelose gel electrophoresi and thiobartital spectrophotometry. The results showed that panax notoginseng saponins could scaven * OH, O2*- efficiently and protect DNA chains from being damaged by hydroxyl radical.
采用分光光度法研究了三七皂苷对芬顿反应体系、邻苯三酚自氧化体系和核黄素光敏化体系中活性氧的清除作用。采用琼脂糖凝胶电泳和硫代巴比妥酸分光光度法观察三七皂苷对羟自由基诱导的DNA链损伤的抑制作用。结果表明，三七皂苷能有效清除·OH、O2-，保护DNA链免受羟自由基的损伤。
