Ganal Martin W, Altmann Thomas, Röder Marion S
TraitGenetics GmbH, Am Schwabeplan 1b, D-06466 Gatersleben, Germany.
Curr Opin Plant Biol. 2009 Apr;12(2):211-7. doi: 10.1016/j.pbi.2008.12.009. Epub 2009 Jan 29.
In many plants, single nucleotide polymorphism (SNP) markers are increasingly becoming the marker system of choice. However, for many crop plants there are surprisingly low numbers of validated SNP markers available although they are needed in large numbers for studies regarding genetic variation, linkage mapping, population structure analysis, association genetics, map-based gene isolation, and plant breeding. This review summarizes the current status of SNP marker development technologies for major crop plants. It will also provide an outlook into the future regarding possible SNP identification approaches in crop plants on the basis of current development in model systems such as Arabidopsis which will become available with the full sequencing of more plant genomes, genome resequencing, and in conjunction with the next-generation sequencing technologies.
在许多植物中,单核苷酸多态性(SNP)标记正日益成为首选的标记系统。然而,对于许多农作物而言,尽管在遗传变异、连锁图谱构建、群体结构分析、关联遗传学、图位克隆基因分离及植物育种等研究中需要大量的SNP标记,但目前经过验证的SNP标记数量却出奇地少。本文综述了主要农作物SNP标记开发技术的现状。基于拟南芥等模式系统的当前发展情况,随着更多植物基因组的全测序、基因组重测序以及与新一代测序技术相结合,本文还将对未来农作物中可能的SNP鉴定方法进行展望。