Eshmanova A K, Luchinskaia E S, Baevskiĭ R M
Aviakosm Ekolog Med. 2008 Sep-Oct;42(5):45-51.
The paper presents the results of investigations into vegetative regulation of blood circulation and regulation modification by peroral amlodipine and myostimulation during 7-d dry immersion. It was shown that in immersion vegetative regulation readjusted towards predominance of the sympathetic mechanisms. Myostimulation and peroral amlodipine modified regulation substantially mobilizing high level suprasegmentary structures. It should be noted that amlodipine and myostimulation differ in mechanisms of their action on central regulation. Pharmaceutical intervention seems to have a more complex and varying effect on people including side-effects. Presumably, it was the cause of poor orthostatic tolerance of several test-subjects.
本文介绍了在7天的干浸过程中,关于血液循环的自主调节以及口服氨氯地平和肌肉刺激对调节的影响的研究结果。结果表明,在浸浴过程中,自主调节向交感神经机制占优势的方向重新调整。肌肉刺激和口服氨氯地平对调节有显著影响,可大量调动高级中枢结构。需要注意的是,氨氯地平和肌肉刺激对中枢调节的作用机制不同。药物干预对人体的影响似乎更为复杂且多样,包括副作用。据推测,这就是部分受试者直立耐力差的原因。