甲苯咪唑在除土源性蠕虫引起的感染之外的寄生虫感染中的应用。
Mebendazole in parasitic infections other than those caused by soil-transmitted helminths.
作者信息
Cañete R, Escobedo A A, Almirall P, González M E, Brito K, Cimerman S
机构信息
Center for Hygiene, Epidemiology and Microbiology, Matanzas City, Cuba.
出版信息
Trans R Soc Trop Med Hyg. 2009 May;103(5):437-42. doi: 10.1016/j.trstmh.2008.11.029. Epub 2009 Feb 4.
Mebendazole, a benzimidazole carbamate compound, is currently in use for human medical practice against soil-transmitted helminthiasis (STH) and enterobiasis. However, it has been demonstrated that its spectrum of activity is broad and goes beyond those infections. Several studies provide evidence that this drug, taken at higher doses than used for STH and enterobiasis, could be sufficiently effective on some protozoa, nematodes and cestodes.
甲苯咪唑是一种氨基甲酸苯并咪唑化合物，目前在人类医学实践中用于治疗土壤传播的蠕虫病（STH）和蛲虫病。然而，已经证明其活性谱很广，超出了这些感染的范围。几项研究提供了证据，表明这种药物在服用剂量高于治疗STH和蛲虫病的剂量时，可能对某些原生动物、线虫和绦虫有足够的疗效。
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