Wadley Virginia G, Okonkwo Ozioma, Crowe Michael, Vance David E, Elgin Jennifer M, Ball Karlene K, Owsley Cynthia
Department of Medicine, Alzheimer's Disease Research Center, University of Alabama at Birmingham School of Medicine, Birmingham, Alabama 35294, USA.
J Geriatr Psychiatry Neurol. 2009 Jun;22(2):87-94. doi: 10.1177/0891988708328215. Epub 2009 Feb 4.
Mild Cognitive Impairment (MCI) involves subtle functional losses that may include decrements in driving skills. We compared 46 participants with MCI to 59 cognitively normal controls on a driving evaluation conducted by a driving rehabilitation specialist who was blinded to participants' MCI classification. Participants with MCI demonstrated significantly lower performance than controls on ratings of global and discrete driving maneuvers, but these differences were not at the level of frank impairments. Rather, performance was simply less than optimal, which to a lesser degree was also characteristic of a subset of the cognitively normal control group. The finding of significantly lower global driving ratings, coupled with the increased incidence of dementia among people with MCI and the known impact of dementia on driving safety, suggests the need for increased vigilance among clinicians, family members, and individuals with MCI for initially benign changes in driving that may become increasingly problematic over time.
轻度认知障碍（MCI）涉及细微的功能丧失，可能包括驾驶技能下降。我们将46名MCI参与者与59名认知正常的对照组进行比较，由一位对参与者MCI分类不知情的驾驶康复专家进行驾驶评估。在整体和离散驾驶操作评分方面，MCI参与者的表现明显低于对照组，但这些差异未达到明显损伤的程度。相反，表现只是未达到最佳水平，在一定程度上这也是认知正常对照组的一个子集的特征。整体驾驶评分显著较低的发现，再加上MCI患者中痴呆症发病率的增加以及痴呆症对驾驶安全的已知影响，表明临床医生、家庭成员和MCI患者需要提高警惕，关注驾驶方面最初看似良性但可能随时间变得越来越成问题的变化。
