School of Aging Studies, 4202 E. Fowler Ave, MHC 1306, Tampa, FL 33620, USA.
J Gerontol B Psychol Sci Soc Sci. 2010 May;65B(3):306-16. doi: 10.1093/geronb/gbq003. Epub 2010 Feb 10.
Studies have found that adults with possible mild cognitive impairment (MCI) exhibit decrements in everyday functioning (e.g., Wadley, V. G., Crowe, M., Marsiske, M., Cook, S. E., Unverzagt, F. W., Rosenberg, A. L., et al. (2007). Changes in everyday function among individuals with psychometrically defined mild cognitive impairment. Journal of the American Geriatrics Society, 55, 1192-1198). However, it is not known whether driving mobility and life space mobility are reduced in such individuals. The current study examined 5-year trajectories of mobility change in older adults (N = 2,355) with psychometrically defined MCI from the Advanced Cognitive Training for Independent and Vital Elderly trial. Mixed effect models evaluated group differences for the following mobility outcomes: driving space, life space, driving frequency, and driving difficulty. Relative to cognitively normal participants, participants with possible MCI showed reduced baseline mobility for all outcomes as well as faster rates of decline for driving frequency and difficulty. These results suggest that mobility declines could be features of MCI, and changes in mobility may be particularly important for researchers and clinicians to monitor in this population.
研究发现，有轻度认知障碍（MCI）可能的成年人在日常功能（例如，Wadley，VG，Crowe，M.，Marsiske，M.，Cook，SE，Unverzagt，FW，Rosenberg，AL等，2007）表现出日常功能下降。（2007）。具有计量学定义的轻度认知障碍的个体中日常功能的变化。美国老年医学会杂志，55，1192-1198）。但是，尚不清楚此类人群的驾驶机动性和生活空间机动性是否降低。本研究检查了来自高级认知训练独立和重要老年人试验的认知上有定义的 MCI 老年人（N = 2355）的 5 年移动性变化轨迹。混合效应模型评估了以下移动性结果的组间差异：驾驶空间，生活空间，驾驶频率和驾驶难度。与认知正常的参与者相比，可能患有 MCI 的参与者在所有结果上的基线移动性均较低，并且驾驶频率和难度的下降速度更快。这些结果表明，移动性下降可能是 MCI 的特征，并且在该人群中，移动性的变化可能对研究人员和临床医生特别重要。
