女性性伴侣共有的生殖道乳酸杆菌菌株分布。
Distribution of genital Lactobacillus strains shared by female sex partners.
作者信息
Marrazzo Jeanne M, Antonio May, Agnew Kathy, Hillier Sharon L
机构信息
Department of Medicine, University of Washington, Seattle, Washington, USA.
出版信息
J Infect Dis. 2009 Mar 1;199(5):680-3. doi: 10.1086/596632.
Abstract
The prevalence of bacterial vaginosis among lesbians is high. We assessed whether unique Lactobacillus strains were shared by female sex partners. Cultures of vaginal and rectal specimens for detection of Lactobacillus organisms were performed for women who reported having had sex with women. Lactobacilli were identified on the basis of DNA homology and were typed and fingerprinted by repetitive element sequence-based polymerase chain reaction (rep-PCR). Of 237 women, Lactobacillus crispatus was detected in 98% and Lactobacillus gasseri in 21%. Detection of L. gasseri was associated with recent receptive digital-vaginal sex (P = .04) and increased bacterial vaginosis risk (odds ratio, 4.2; 95% confidence interval, 1.4-13.4). Of 31 couples monogamous for >3 months, rep-PCR fingerprints were identical in both members in 23 (77%).
摘要
女同性恋者中细菌性阴道病的患病率很高。我们评估了女性性伴侣之间是否共享独特的乳酸杆菌菌株。对报告与女性发生过性行为的女性进行阴道和直肠标本培养，以检测乳酸杆菌。根据DNA同源性鉴定乳酸杆菌，并通过基于重复元件序列的聚合酶链反应（rep-PCR）进行分型和指纹识别。在237名女性中，98%检测到卷曲乳酸杆菌，21%检测到加氏乳酸杆菌。检测到加氏乳酸杆菌与近期接受指交-阴道性行为有关（P = .04），且细菌性阴道病风险增加（优势比，4.2；95%置信区间，1.4 - 13.4）。在31对一夫一妻制关系持续超过3个月的伴侣中，23对（77%）双方的rep-PCR指纹相同。
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