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寒冷可防止光诱导的黑线毛足鼠(Phodopus sungorus)松果体N-乙酰转移酶失活。

Cold prevents the light induced inactivation of pineal N-acetyltransferase in the Djungarian hamster, Phodopus sungorus.

作者信息

Stieglitz A, Steinlechner S, Ruf T, Heldmaier G

机构信息

Department of Biology/Zoology, Philipps-University, Marburg, Germany.

出版信息

J Comp Physiol A. 1991 May;168(5):599-603. doi: 10.1007/BF00215082.

DOI:10.1007/BF00215082
PMID:1920160
Abstract

In the Djungarian hamster seasonal acclimatization is primarily controlled by photoperiod, but exposure to low ambient temperature amplifies the intensity and duration of short day-induced winter adaptations. The aim of this study was to test, whether the pineal gland is involved in integrating both environmental cues. Exposure of hamsters to cold (0 degrees C) reduces the sensitivity of the pineal gland to light at night and prevents inactivation of N-acetyltransferase (NAT). The parallel time course of NAT activity and plasma norepinephrine content suggests that circulating catecholamines may stimulate melatonin synthesis under cold load.

摘要

在西伯利亚仓鼠中,季节性适应主要受光周期控制,但暴露于低环境温度会增强短日照诱导的冬季适应性的强度和持续时间。本研究的目的是测试松果体是否参与整合这两种环境信号。将仓鼠暴露于寒冷环境(0摄氏度)会降低松果体在夜间对光的敏感性,并阻止N-乙酰转移酶(NAT)失活。NAT活性和血浆去甲肾上腺素含量的平行时间进程表明,循环中的儿茶酚胺可能在冷负荷下刺激褪黑素的合成。

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本文引用的文献

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Seasonal pattern and energetics of short daily torpor in the Djungarian hamster, Phodopus sungorus.黑线毛足鼠(Phodopus sungorus)每日短时间蛰伏的季节性模式与能量学
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Sensitive assay for serotonin N-acetyltransferase activity in rat pineal.大鼠松果体中血清素N-乙酰基转移酶活性的灵敏测定法。
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Control of pineal indole biosynthesis by changes in sympathetic tone caused by factors other than environmental lighting.除环境光照外的其他因素引起的交感神经张力变化对松果体吲哚生物合成的调控。
Proc Natl Acad Sci U S A. 1973 Jun;70(6):1704-7. doi: 10.1073/pnas.70.6.1704.