Brooks B O, Utter G M, DeBroy J A, Schimke R D
Health Effects Research Department, IBM Corporation Boulder, Colorado 80302.
J Toxicol Clin Toxicol. 1991;29(3):315-74. doi: 10.3109/15563659109000363.
The collision of escalating technological sophistication and surging environmental awareness has caused the reexamination of many societal paradigms. Horror stories about lethal chemical exposures involving isolated cases of ignorance, carelessness or greed have caused the public to demand constant vigilance to prevent exposure to potentially hazardous substances. Accordingly, much time and resource has been expanded by the U.S. government and citizens to abate and prevent air and water pollution. While these efforts have met with measurable success, there is increasing public concern about a new generation of pollution-related human illness in office, home and transportation environments. New instances of Sick Building Syndrome or Building Related Illness are reported daily by the popular press. Human health effects such as cancer, infectious disease, allergy and irritation have been ascribed to indoor air pollution. The clinical aspects of indoor air pollution are often discounted by consulting engineers and industrial hygienists involved in indoor air quality. Physicians and clinically-trained scientists have received a "Macedonian call" to sift clinical relevance from the emotional aspects of indoor air quality problems. Point sources of pollutants, associated human health effects, and problem solving approaches associated with indoor air pollution are described. Regulatory and litigational aspects of indoor air pollution are also discussed.
技术复杂性不断提高与环境意识不断增强的碰撞，引发了对许多社会范式的重新审视。关于致命化学物质暴露的恐怖故事，涉及个别无知、粗心或贪婪的案例，这使得公众要求保持持续警惕，以防止接触潜在有害物质。因此，美国政府和公民投入了大量时间和资源来减少和防止空气和水污染。虽然这些努力取得了显著成效，但公众越来越关注办公室、家庭和交通环境中与污染相关的新一代人类疾病。大众媒体每天都报道病态建筑综合征或与建筑相关疾病的新案例。癌症、传染病、过敏和刺激等人类健康影响已被归因于室内空气污染。参与室内空气质量的咨询工程师和工业卫生学家往往忽视室内空气污染的临床方面。医生和受过临床培训的科学家接到了“马其顿式的召唤”，要从室内空气质量问题的情感方面筛选出临床相关性。本文描述了污染物的点源、相关的人类健康影响以及与室内空气污染相关的解决问题方法。还讨论了室内空气污染的监管和诉讼方面。
