School of Behavioral and Brain Sciences, The University of Texas at Dallas, Richardson, TX, USA.
Arch Clin Neuropsychol. 2014 Feb;29(1):16-25. doi: 10.1093/arclin/act089. Epub 2013 Dec 8.
The authors first examined the concurrent moderating role of lifestyle engagement on the relation between cognitive status (cognitively elite, cognitively normal [CN], and cognitively impaired [CI]) and executive functioning (EF) in older adults. Second, the authors examined whether baseline participation in lifestyle activities predicted differential 4.5-year stabilities and transitions in cognitive status. Participants (initial N = 501; 53-90 years) were from the Victoria Longitudinal Study. EF was represented by a 1-factor structure. Lifestyle activities were measured in multiple domains of engagement (e.g., cognitive, physical, and social). Two-wave status stability groups included sustained normal aging, transitional early impairment, and chronic impairment. Hierarchical regressions showed that baseline participation in social activities moderated cognitive status differences in EF. CI adults with high (but not low) social engagement performed equivalently to CN adults on EF. Longitudinally, logistic regressions showed that engagement in physical activities was a significant predictor of stability of cognitive status. CI adults who were more engaged in physical activities were more likely to improve in their cognitive status over time than their more sedentary peers. Participation in cognitive activities was a significant predictor of maintenance in a higher cognitive status group. Given that lifestyle engagement plays a detectable role in healthy, normal, and impaired neuropsychological aging, further research in activity-related associations and interventions is recommended.
作者首先考察了生活方式参与对认知状态(认知精英、认知正常[CN]和认知受损[CI])与执行功能(EF)之间关系的并发调节作用。其次,作者考察了基线参与生活方式活动是否预测认知状态的 4.5 年稳定性和转变的差异。参与者(初始 N = 501;53-90 岁)来自维多利亚纵向研究。EF 由 1 个因素结构表示。生活方式活动在多个参与领域进行测量(例如认知、身体和社会)。两波状态稳定性组包括持续正常衰老、早期过渡性损伤和慢性损伤。层次回归显示,基线参与社会活动调节了 EF 中认知状态的差异。高(但不低)社会参与的 CI 成年人在 EF 上与 CN 成年人表现相当。纵向分析显示,身体活动的参与是认知状态稳定性的一个显著预测因素。与久坐不动的同龄人相比,更积极参与身体活动的 CI 成年人随着时间的推移更有可能改善他们的认知状态。参与认知活动是维持更高认知状态组的一个显著预测因素。鉴于生活方式参与在健康、正常和受损的神经心理衰老中发挥着可检测的作用,建议进一步研究与活动相关的关联和干预措施。