Department of Neurobiology, Institute of Neuroscience, The Fourth Military Medical University, Xian, The People's Republic of China.
J Neuroendocrinol. 1989 Dec 1;1(6):397-400. doi: 10.1111/j.1365-2826.1989.tb00137.x.
Abstract In a previous study, substance P-immunoreactive nerve fibers were demonstrated in the pars distalis of the anterior pituitary in the monkey. The present work investigated their relationship with somatotropes. Pituitaries of Macaca mulatta monkeys were frozen, sectioned and double immunostained with antisera against substance P and human growth hormone. Substance P-immunoreactive nerve fibers, with many varicosities, were found in close proximity to somatotropes. It is suggested that a direct neural factor may be involved in the regulation of growth hormone secretion.
在之前的研究中，已经在猴的垂体前叶远侧部发现了具有 P 物质免疫反应性的神经纤维。本工作研究了它们与生长激素细胞的关系。使用抗 P 物质和人生长激素的抗体对猕猴的垂体进行双重免疫染色，结果发现具有许多膨体的 P 物质免疫反应性神经纤维与生长激素细胞紧密相邻。这表明生长激素分泌的调节可能涉及直接的神经因素。
