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Setting the pace: Tbx3 and Tbx18 in cardiac conduction system development.

作者信息

McNally Elizabeth M, Svensson Eric C

出版信息

Circ Res. 2009 Feb 13;104(3):285-7. doi: 10.1161/CIRCRESAHA.109.193680.

Abstract
摘要

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The anatomy of the cardiac conduction system.
Clin Anat. 2009 Jan;22(1):99-113. doi: 10.1002/ca.20700.
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A myocardial lineage derives from Tbx18 epicardial cells.
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Transcription factor Tbx3 is required for the specification of the atrioventricular conduction system.
Circ Res. 2008 Jun 6;102(11):1340-9. doi: 10.1161/CIRCRESAHA.107.169565. Epub 2008 May 8.
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Targeted mutation reveals essential functions of the homeodomain transcription factor Shox2 in sinoatrial and pacemaking development.
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