泰国的传统药用植物。第十七部分。鸡蛋花的生物活性成分。
Traditional medicinal plants of Thailand. XVII. Biologically active constituents of Plumeria rubra.
作者信息
Hamburger M O, Cordell G A, Ruangrungsi N
机构信息
Program for Collaborative Research in the Pharmaceutical Sciences, College of Pharmacy, University of Illinois, Chicago 60612.
出版信息
J Ethnopharmacol. 1991 Jul;33(3):289-92. doi: 10.1016/0378-8741(91)90091-q.
The compounds 1-6 were isolated from the heartwood of Plumeria rubra, following bioactivity-directed fractionation. Plumericin 1 and isoplumericin 2 displayed molluscicidal, cytotoxic and antibacterial activity, 4-hydroxyacetophenone 3 was weakly cytotoxic, whereas the remaining glycosidic isolates (plumieride, 4; 13-O-coumaroylplumieride, 5; protoplumericine A, 6) were inactive in all test systems.
化合物1-6是从鸡蛋花的心材中通过生物活性导向分离得到的。鸡蛋花素1和异鸡蛋花素2具有杀螺、细胞毒性和抗菌活性，4-羟基苯乙酮3具有较弱的细胞毒性，而其余糖苷类分离物（鸡蛋花苷，4；13-O-香豆酰鸡蛋花苷，5；原鸡蛋花素A，6）在所有测试系统中均无活性。
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