Awanchiri Simon Suh, Trinh-Van-Dufat Hanh, Shirri Jovita Chi, Dongfack Marlise Diane J, Nguenang Guy Merlin, Boutefnouchet Sabrina, Fomum Zacharias T, Seguin Elisabeth, Verite Philippe, Tillequin François, Wandji Jean
Department of Organic Chemistry, University of Yaounde-1, Faculty of Science, P.O. Box 812, Yaounde, Cameroon.
Phytochemistry. 2009 Feb;70(3):419-23. doi: 10.1016/j.phytochem.2008.12.017. Epub 2009 Feb 13.
The air-dried stems and ripe fruit of Drypetes inaequalis Hutch. (Euphorbiaceae) were studied. Four triterpene derivatives, characterized as lup-20(29)-en-3beta,6alpha-diol, 3beta-acetoxylup-20(29)-en-6alpha-ol, 3beta-caffeoyloxylup-20(29)-en-6alpha-ol and 28-betad-glucopyranosyl-30-methyl 3beta-hydroxyolean-12-en-28,30-dioate along with 10 known compounds were isolated from the whole stems. One triterpene, characterized as 3alpha-hydroxyfriedelan-25-al along with six known compounds were isolated from the ripe fruit. Their structures were established on the basis of spectroscopic analysis and chemical evidence. The triterpenes were tested for antimicrobial activity against some Gram-positive and Gram-negative bacteria, and two of them appeared to be modestly active.
对哈钦森核果木（大戟科）的风干茎和成熟果实进行了研究。从整个茎中分离出四种三萜衍生物，分别鉴定为羽扇 -20(29)-烯 -3β,6α -二醇、3β -乙酰氧基羽扇 -20(29)-烯 -6α -醇、3β -咖啡酰氧基羽扇 -20(29)-烯 -6α -醇和28 -β -D -吡喃葡萄糖基 -30 -甲基3β -羟基齐墩果 -12 -烯 -28,30 -二酸酯，以及10种已知化合物。从成熟果实中分离出一种三萜，鉴定为3α -羟基木栓烷 -25 -醛，以及六种已知化合物。它们的结构是根据光谱分析和化学证据确定的。对这些三萜进行了针对一些革兰氏阳性和革兰氏阴性细菌的抗菌活性测试，其中两种表现出一定的活性。
