Borovik Armand M, Bosch Martina M, Watson Stephanie L
Department of Ophthalmology, Prince of Wales Hospital, Sydney, NSW, Australia.
Med J Aust. 2009 Feb 16;190(4):210-1. doi: 10.5694/j.1326-5377.2009.tb02353.x.
A 55-year-old woman who was treated with long-term, high-dose clozapine for schizophrenia presented with bilateral decreased visual acuity. She had pigmentary changes affecting the cornea and the retina, as well as stellate cataract. Chlorpromazine use is known to produce similar changes, but this is the first report to our knowledge of pigmentation associated with clozapine use.
一名55岁女性因精神分裂症接受长期大剂量氯氮平治疗，出现双侧视力下降。她有影响角膜和视网膜的色素沉着变化，以及星状白内障。已知使用氯丙嗪会产生类似变化，但据我们所知，这是首例与使用氯氮平相关的色素沉着报告。
