Ness Kirsten K, Leisenring Wendy M, Huang Sujuan, Hudson Melissa M, Gurney James G, Whelan Kimberly, Hobbie Wendy L, Armstrong Gregory T, Robison Leslie L, Oeffinger Kevin C
Department of Epidemiology and Cancer Control, St. Jude Children's Research Hospital, Memphis, Tennessee, USA.
Cancer. 2009 May 1;115(9):1984-94. doi: 10.1002/cncr.24209.
: Participation in physical activity is important for childhood cancer survivors, because inactivity may compound cancer/treatment-related late effects. However, some survivors may have difficulty participating in physical activity, and these individuals need to be identified so that risk-based guidelines for physical activity, tailored to specific needs, can be developed and implemented. The objectives of the current study were to document physical activity patterns in the Childhood Cancer Survivor Study (CCSS) cohort, to compare the physical activity patterns with siblings in the CCSS and with a population-based sample from the Behavioral Risk Factor Surveillance System, and to evaluate associations between diagnosis, treatment, and personal factors in terms of the risk for an inactive lifestyle.
: Percentages of participation in recommended physical activity were compared among survivors, siblings, and population norms. Generalized linear models were used to evaluate the associations between cancer diagnosis and therapy, sociodemographics, and the risk for an inactive lifestyle.
: Participants included 9301 adult survivors of childhood cancer and 2886 siblings. Survivors were less likely than siblings (46% vs 52%) to meet physical activity guidelines and were more likely than siblings to report an inactive lifestyle (23% vs 14%). Medulloblastoma (35%) and osteosarcoma (27%) survivors reported the highest levels of inactive lifestyle. Treatments with cranial radiation or amputation were associated with an inactive lifestyle as were being a woman, black race, older age, lower educational attainment, underweight or obese status, smoking, and depression.
: Childhood cancer survivors were less active than a sibling comparison group or an age- and sex-matched population sample. Survivors who are at risk for an inactive lifestyle should be considered high priority for developing and testing of intervention approaches. Cancer 2009. (c) 2009 American Cancer Society.
参与体育活动对儿童癌症幸存者很重要，因为缺乏运动会加重癌症/治疗相关的晚期效应。然而，一些幸存者可能在参与体育活动方面存在困难，需要识别出这些个体，以便制定并实施针对特定需求的基于风险的体育活动指南。本研究的目的是记录儿童癌症幸存者研究（CCSS）队列中的体育活动模式，将该队列中的体育活动模式与CCSS中的兄弟姐妹以及行为危险因素监测系统中基于人群的样本进行比较，并从久坐生活方式风险的角度评估诊断、治疗和个人因素之间的关联。
比较幸存者、兄弟姐妹和人群标准中参与推荐体育活动的百分比。使用广义线性模型评估癌症诊断与治疗、社会人口统计学与久坐生活方式风险之间的关联。
参与者包括9301名儿童癌症成年幸存者和2886名兄弟姐妹。幸存者比兄弟姐妹更不可能达到体育活动指南的要求（46%对52%），并且比兄弟姐妹更有可能报告久坐的生活方式（23%对14%）。髓母细胞瘤（35%）和骨肉瘤（27%）幸存者报告的久坐生活方式水平最高。接受颅脑放疗或截肢治疗与久坐生活方式相关，女性、黑人、年龄较大、教育程度较低、体重过轻或肥胖、吸烟和抑郁也与久坐生活方式相关。
儿童癌症幸存者的活动量低于兄弟姐妹对照组或年龄和性别匹配的人群样本。对于久坐生活方式有风险的幸存者，应被视为开发和测试干预方法的高度优先对象。癌症2009。（c）2009美国癌症协会。
