Liu Jian-Qun, Wu Ji-Mei, Kou Xiao-Li, Hong Qin
Key Laboratory of Modern Preparation of TCM, Ministry of Education, Jiangxi University of Traditional Chinese Medicine, Nanchang 330004, China.
Zhong Yao Cai. 2008 Oct;31(10):1505-7.
To investigate the chemical constituents of Grewia biloba and find its bioactive compounds.
Compounds were isolated by silica gel, MCI, Sephadex LH-20 and Rp-18 column chromatography, and purified by recrystallization. Their structures were elucidated by spectral analysis and other methods.
Six compounds were isolated and identified as friedelin (1) epi-friedelan-3-ol (2), heneicosanoic acid (3), beta-sitosterol (4), Propyl palmitate (5), eatechin (6), respectively.
Compounds 1-3, 5, 6 are isolated from Grewia genus for the first time and compounds 4 is isolated from Grewia biloba for the first time.
研究扁担杆的化学成分并寻找其生物活性化合物。
通过硅胶柱色谱、MCI柱色谱、葡聚糖凝胶LH - 20柱色谱和Rp - 18柱色谱分离化合物，并通过重结晶进行纯化。采用光谱分析等方法阐明其结构。
分离鉴定出6种化合物，分别为蛇麻脂醇（1）、表蛇麻脂醇 - 3 - 醇（2）、二十一烷酸（3）、β - 谷甾醇（4）、棕榈酸丙酯（5）、儿茶素（6）。
化合物1 - 3、5、6首次从扁担杆属植物中分离得到，化合物4首次从扁担杆中分离得到。
