Kallings Lena V, Sierra Johnson Justo, Fisher Rachel M, Faire Ulf de, Ståhle Agneta, Hemmingsson Erik, Hellénius Mai-Lis
Department of Neurobiology, Health Care Sciences and Society, Karolinska Institutet, Huddinge, Sweden.
Eur J Cardiovasc Prev Rehabil. 2009 Feb;16(1):80-4. doi: 10.1097/HJR.0b013e32831e953a.
Insufficient physical activity (PA), overweight and abdominal obesity are increasing global public health problems.
Randomized controlled 6-month intervention study.
One hundred and one 68-year-old individuals (57% female) with low PA, overweight (BMI 25-40 kg/m) and abdominal obesity (waist circumference >88 cm in women and >102 cm in men), were randomized to PA on prescription (PAP) or a minimal intervention. PA measured by several methods, anthropometric parameters, body composition and cardiometabolic risk factors were measured at baseline and after intervention.
Favourable changes in anthropometrics, body composition, S-glucose, glycosolated haemoglobin (HbA1c), blood lipids and apolipoproteins were seen in the PAP group. In the control group, however, some positive changes were also noted. Bodyweight, neck circumference, fat mass, S-cholesterol and HbA1c decreased significantly more in the PAP group.
Individualized PAP improves body composition and cardiometabolic risk factors in sedentary older overweight individuals. PAP might be useful in clinical practice to counteract the epidemic of sedentary lifestyle and concomitant cardiometabolic disorders.
身体活动不足、超重和腹型肥胖是日益严重的全球公共卫生问题。
为期6个月的随机对照干预研究。
101名68岁的个体（57%为女性），身体活动水平低、超重（体重指数25 - 40 kg/m）且腹型肥胖（女性腰围>88 cm，男性腰围>102 cm），被随机分为处方身体活动组（PAP）或最小干预组。在基线和干预后，通过多种方法测量身体活动、人体测量参数、身体成分和心血管代谢危险因素。
PAP组在人体测量、身体成分、空腹血糖、糖化血红蛋白（HbA1c）、血脂和载脂蛋白方面出现了有利变化。然而，在对照组中也观察到了一些积极变化。PAP组的体重、颈围、脂肪量、总胆固醇和HbA1c下降幅度明显更大。
个体化的PAP可改善久坐不动的老年超重个体的身体成分和心血管代谢危险因素。PAP在临床实践中可能有助于应对久坐生活方式流行及随之而来的心血管代谢紊乱问题。
