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作为全球哮喘防治创议(GINA)指南定义的哮喘控制指标预测工具的哮喘控制测试(ACT):一项跨国横断面调查分析

The Asthma Control Test (ACT) as a predictor of GINA guideline-defined asthma control: analysis of a multinational cross-sectional survey.

作者信息

Thomas Mike, Kay Stephen, Pike James, Williams Angela, Rosenzweig Jacqueline R Carranza, Hillyer Elizabeth V, Price David

机构信息

Centre of Academic Primary Care, University of Aberdeen, Scotland, UK.

出版信息

Prim Care Respir J. 2009 Mar;18(1):41-9. doi: 10.4104/pcrj.2009.00010.

DOI:10.4104/pcrj.2009.00010
PMID:19240948
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6619040/
Abstract

AIMS

To evaluate whether the Asthma Control Test (ACT) score is predictive of Global Initiative for Asthma (GINA) guideline-defined classification levels of asthma control. The ACT is a validated, 5-item, patient-completed measure of asthma control with a recall period of four weeks.

METHODS

Cross-sectional survey comparing ACT score and GINA classification of asthma control among 2949 patients attending primary care physicians and specialists in France, Germany, Italy, Spain, the UK, and the USA.

RESULTS

The area under the receiver operating characteristics curve for ACT score predicting GINA control was 0.84 (95% CI 0.82-0.85). An ACT score of <19 (not well-controlled asthma) correctly predicted GINA-defined partly controlled/uncontrolled asthma 94% of the time, while an ACT score of >20 predicted GINA-defined controlled asthma 51% of the time, with kappa statistic of 0.42, representing moderate agreement.

CONCLUSIONS

An ACT score <19 is useful for identifying patients with poorly controlled asthma as defined by GINA.

摘要

目的

评估哮喘控制测试(ACT)分数是否能预测全球哮喘防治创议(GINA)指南定义的哮喘控制分级水平。ACT是一项经过验证的、由患者自行完成的5项哮喘控制指标,回顾期为四周。

方法

在法国、德国、意大利、西班牙、英国和美国,对2949名就诊于初级保健医生和专科医生的患者进行横断面调查,比较ACT分数与GINA哮喘控制分级。

结果

ACT分数预测GINA控制情况的受试者工作特征曲线下面积为0.84(95%置信区间0.82 - 0.85)。ACT分数<19(哮喘控制不佳)时,94%的情况下能正确预测GINA定义的部分控制/未控制哮喘;ACT分数>20时,51%的情况下能预测GINA定义的控制良好哮喘,kappa统计量为0.42,代表中度一致性。

结论

ACT分数<19有助于识别GINA定义的哮喘控制不佳患者。