Bezanilla Magdalena, Wadsworth Pat
Department of Biology, University of Massachusetts Amherst, 01003, USA.
Curr Biol. 2009 Feb 24;19(4):R168-9. doi: 10.1016/j.cub.2008.12.026.
To divide asymmetrically, the mitotic spindle is moved from the cell center to the cortex, a process that requires astral microtubules and the microtubule-based motor dynein. New work examining spindle positioning in large oocytes shows that in these cells actin and actin polymerization plays a key role.
为了进行不对称分裂,有丝分裂纺锤体从细胞中心移至皮层,这一过程需要星体微管以及基于微管的动力蛋白。一项研究大型卵母细胞中纺锤体定位的新工作表明,在这些细胞中,肌动蛋白及肌动蛋白聚合发挥着关键作用。