Hasenfratz M, Bättig K
Comparative Physiology and Behavioral Biology Laboratory, ETH-Zentrum, Zurich, Switzerland.
Psychopharmacology (Berl). 1991;104(3):356-62. doi: 10.1007/BF02246036.
This study investigated the effects of 9 days' smoking abstinence on psychophysiological stress reactions. The subjects were 40 female smokers; 20 of them intended to give up smoking in the course of the study, whereas the remaining 20 had no such intention. A first session was carried out before, a second and a third during days 3 and 9 of abstinence. The nonabstainers were tested at corresponding intervals. Each session consisted of a 30-min stress-coping phase with relaxation phases before and after. While performing a rapid information processing task (RIP) the subjects had to sustain electrical shocks which were, according to instructions, but not in fact, either avoidable (active coping) or not (passive coping). Generally, the active coping instruction produced greater responses to the RIP task than did the passive coping instruction for heart rate, systolic and diastolic blood pressure but not for finger pulse amplitude, thus resembling a beta-adrenergic stimulation. RIP processing rate was not affected, but the response rate (total of hits and commission errors) was greater during active than during passive coping. However, none of these stress reactions differed between abstainers and nonabstainers. On the other hand, both heart rate and the craving to smoke decreased significantly in the abstainer group across the 9 days. Thus, it is concluded that a deprivation of 1 h, 3 or 9 days has no differential effect on physiological stress reactions.
本研究调查了9天戒烟对心理生理应激反应的影响。受试者为40名女性吸烟者;其中20人打算在研究过程中戒烟,而其余20人则没有此打算。在戒烟前进行了第一次测试,在戒烟第3天和第9天分别进行了第二次和第三次测试。对未戒烟者在相应的时间间隔进行测试。每次测试包括一个30分钟的应激应对阶段,前后各有放松阶段。在执行快速信息处理任务(RIP)时,受试者必须承受电击,根据指示,这些电击在实际中要么是可避免的(主动应对),要么是不可避免的(被动应对)。一般来说,主动应对指令对心率、收缩压和舒张压产生的RIP任务反应比被动应对指令更大,但对手指脉搏幅度没有影响,因此类似于β-肾上腺素能刺激。RIP处理率不受影响,但主动应对时的反应率(命中和错误总数)比被动应对时更高。然而,这些应激反应在戒烟者和未戒烟者之间没有差异。另一方面,戒烟者组的心率和吸烟渴望在9天内均显著下降。因此,得出的结论是,1小时、3天或9天的戒烟对生理应激反应没有差异影响。