Regional Medical Physics Department, Dryburn Hospital, Durham DH1 5TW, UK.
Int J Cosmet Sci. 1994 Apr;16(2):47-52. doi: 10.1111/j.1467-2494.1994.tb00082.x.
Synopsis A method is described and evaluated for classifying sunscreen products into different broad spectrum categories. The method is based on spectrophotometric analysis of products applied to a suitable substrate and obviates the need for human or animal studies utilizing clinical endpoints which may be of dubious value in relation to protection from sun exposure. The absorbance spectrum obtained by spectrophotometric assay is reduced to a single index by determining that wavelength lambda(c) where the area under the spectrum from 290 nm (the approximate lower wavelength limit of terrestrial sunlight) to lambda(c) is 90% of the integral of the absorbance spectrum from 290 to 400 nm. A five-point scale is used to classify products as follows: The method makes no underlying assumptions about the form of action spectra for either acute or chronic photobiological damage. However, acknowledgement is made of the fact that the efficiency of ultraviolet radiation to induce a given photobiological endpoint tends to decrease with increasing wavelength by adopting wavelength intervals for classifying the Broad Spectrum Rating which increase in an approximately logarithmic manner.
摘要 本文描述并评价了一种将防晒产品分类为不同广谱类别的方法。该方法基于对涂敷于适宜基底的产品的分光光度分析，避免了利用临床终点进行人类或动物研究的需要，这些临床终点与防止阳光暴露相关，其价值可能值得怀疑。通过分光光度法测定，将光谱从 290nm（陆地阳光的近似下限波长）到 lambda(c)的区域下的面积与从 290 到 400nm 的吸收光谱积分的 90%的波长 lambda(c)确定为单一指数，从而将获得的吸收光谱简化为单一指数。使用五分制对产品进行分类：该方法对急性或慢性光生物学损伤的作用光谱形式不做任何基本假设。但是，通过采用广谱评级分类的波长间隔以近似对数方式增加的方式，承认紫外线辐射诱导给定光生物学终点的效率往往随着波长的增加而降低。
